A physical map of the genetic makeup of a mouse - the mouse genome - is 98 percent complete and is being released online by the journal Nature. Researchers at the Genome Sequencing Center at Washington University School of Medicine in St. Louis played a major role in the international effort, as they did in the sequencing and mapping of the human genome.
"The mouse plays a vital role in research on human biology and disease," says John D. McPherson, Ph.D., associate professor of genetics and the lead investigator on the St. Louis team. "This physical map gives us the big picture of the mouse genome. It will be tremendously helpful to medical investigators and to those studying the human genome."
Comparison of the mouse and human maps, for example, can highlight regions of DNA that control genes. These regions are crucial to understanding the role of genes in health and disease, but they are difficult to find using current methods.
Signaling Pathways to the Nucleus
19.03.2018 | Albert-Ludwigs-Universität Freiburg im Breisgau
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19.03.2018 | Max-Planck-Institut für Ornithologie
For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.
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At the 2018 ILA Berlin Air Show from April 25–29, the Fraunhofer Institute for Laser Technology ILT is showcasing extreme high-speed Laser Material Deposition (EHLA): A video documents how for metal components that are highly loaded, EHLA has already proved itself as an alternative to hard chrome plating, which is now allowed only under special conditions.
When the EU restricted the use of hexavalent chromium compounds to special applications requiring authorization, the move prompted a rethink in the surface...
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