It’s widely known that only about one in every 100 HIV viruses can effectively complete the process of integrating its DNA with the DNA of the human cell -- a step that every virus must successfully complete before it can reproduce.
But a new study led by Dr. David N. Levy, an Assistant Professor of Basic Science and Craniofacial Biology at the NYU College of Dentistry, has revealed a mechanism that enables some of the other 99 percent of HIV viruses also to replicate and play a potential role in the development of AIDS.
“We’ve observed a new mode of HIV replication that involves cooperative interaction between viruses,” said Dr. Levy.
According to Dr. Levy, HIV functions as a community, with those viruses that successfully integrate with the DNA in human cells rescuing the viruses that fail to integrate by providing them with the proteins they need to reproduce. In fact, the viruses that were once thought to be lost because they don’t integrate may have an advantage over the others because they can skip several steps in their replication cycle and reproduce faster.
“Cooperation between different viruses is yet another one of the many tricks that HIV uses to survive, and raises the possibility that there are more active viruses in the body than was previously thought. Understanding how viruses interact with each other is a key to understanding how HIV evolves and survives the body’s immune responses, which we hope could ultimately lead to the development of new ways to treat HIV infection.”
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The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
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Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
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Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
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Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
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