It’s widely known that only about one in every 100 HIV viruses can effectively complete the process of integrating its DNA with the DNA of the human cell -- a step that every virus must successfully complete before it can reproduce.
But a new study led by Dr. David N. Levy, an Assistant Professor of Basic Science and Craniofacial Biology at the NYU College of Dentistry, has revealed a mechanism that enables some of the other 99 percent of HIV viruses also to replicate and play a potential role in the development of AIDS.
“We’ve observed a new mode of HIV replication that involves cooperative interaction between viruses,” said Dr. Levy.
According to Dr. Levy, HIV functions as a community, with those viruses that successfully integrate with the DNA in human cells rescuing the viruses that fail to integrate by providing them with the proteins they need to reproduce. In fact, the viruses that were once thought to be lost because they don’t integrate may have an advantage over the others because they can skip several steps in their replication cycle and reproduce faster.
“Cooperation between different viruses is yet another one of the many tricks that HIV uses to survive, and raises the possibility that there are more active viruses in the body than was previously thought. Understanding how viruses interact with each other is a key to understanding how HIV evolves and survives the body’s immune responses, which we hope could ultimately lead to the development of new ways to treat HIV infection.”
Newly designed molecule binds nitrogen
23.02.2018 | Julius-Maximilians-Universität Würzburg
Atomic Design by Water
23.02.2018 | Max-Planck-Institut für Eisenforschung GmbH
A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.
In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...
A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.
By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...
Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
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23.02.2018 | Physics and Astronomy
23.02.2018 | Health and Medicine
23.02.2018 | Physics and Astronomy