The findings of the study, performed at three German universities, may indicate why death due to heart disease has decreased among diabetic men but not in women with type 2 diabetes, said the study’s primary author. Ioanna Gouni-Berthold, MD, professor of medicine at the University of Cologne, led the study.
“Our study shows that in patients with diabetes there is a clear disparity between men and women in the control and treatment of important modifiable risk factors for cardiovascular disease,” Gouni-Berthold said. “Women have worse control of their blood pressure, blood sugar and cholesterol levels compared to men and are given cholesterol-lowering medications less often.”
Gouni-Berthold and researchers from the University of Bonn and University of Homburg studied nearly 45,000 people with type 2 diabetes treated as outpatients by private-practice physicians from 2002 to 2003. Of the patients, 9,521 men and 8,050 women had heart and vascular disease.
There were no gender differences in the intensity of medication management or most heart disease risk factors among diabetic patients who did not have heart disease, the study found. However, in the group with cardiovascular disease, women were 44 percent more likely than men to have high LDL (“bad”) cholesterol, yet 15 percent less likely to receive lipid-lowering medications, the authors reported. Women also were 19 percent more likely than men to have uncontrolled high blood pressure.
In addition, women were 15 percent more likely to have poor long-term control of their blood glucose (sugar) level, as shown by a hemoglobin A1c blood test above 8 percent. The recommended A1c level for adults with type 2 diabetes is less than 7 percent.
The findings are cause for concern, according to Gouni-Berthold, because there is evidence that diabetes cancels the protective effect of female sex on the risk of heart disease.
“More aggressive treatment of cardiovascular disease in women with diabetes may improve the gender disparity in cardiovascular disease mortality,” she said. “Patients should speak with their doctors about the intensity of treatment modalities.”
The study patients were part of the German DUTY (Diabetes mellitus needs unrestricted evaluation of patient data to yield treatment progress) Registry. Merck Sharp & Dohme provided a research grant that funded the registry. However, the pharmaceutical company had no influence on data analysis, according to Gouni-Berthold.
Patrick Honecker | alfa
Research team creates new possibilities for medicine and materials sciences
22.01.2018 | Humboldt-Universität zu Berlin
Saarland University bioinformaticians compute gene sequences inherited from each parent
22.01.2018 | Universität des Saarlandes
On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.
We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
22.01.2018 | Materials Sciences
22.01.2018 | Earth Sciences
22.01.2018 | Life Sciences