The goal of the collaboration is to advance adipose-derived stem and regenerative cells into clinical trials for stroke. The underlying damage in stroke is brought about by a loss of blood flow to the brain.
Because adipose-derived stem and regenerative cells have been shown to improve tissue outcome during injury resulting from a reduction in blood flow, it is believed that these cells could represent a novel approach for reducing stroke-induced damage.
"Our interest in stroke is based on several factors," said Kai Pinkernell, M.D., head of research for Cytori. "First, stroke represents a tremendous unmet medical need, whereby vascular blockages in the brain can result in loss of brain function. Second, because stroke is brought about by a loss of blood supply, we can apply what we already know about restoring blood flow and reducing tissue damage in cardiovascular disease.
Third, timing is thought to be critical in the treatment of stroke and the Celution® 800 System can make a patient's own stem and regenerative cells available in real-time."
The Fraunhofer Institute for Cell Therapy and Immunology will contribute their extensive scientific expertise in neural repair. "In combining the competencies of both partners in regenerative medicine, we will have the promising opportunity to develop a novel therapeutic strategy that might have the potential to beneficially influence functional recovery following ischemic stroke." stated Dr. Johannes Boltze, head of the Neurorepair Research Group at Fraunhofer IZI.
"For this, a step-wise experimental approach including small and large animal studies adhering to the strict STAIR-criteria for stroke therapy development will be utilized." Cytori will contribute their knowledge in adipose-derived stem and regenerative cell biology as it relates to cardiovascular conditions. At the end of the two year term, Cytori will have the opportunity to advance the work into clinical trials and through to commercialization.
"This is the third grant within the last nine months for which we have the privilege to participate," added Dr. Pinkernell. "In addition to the financial support, these grants represent significant validation from government and private organizations in the US, Japan and Germany as a testament to the global interest in regenerative medicine and how adipose-derived stem and regenerative cells may play an important role. As the pioneer in this field, we look forward to working in collaboration with organizations from around the world to bring novel therapies to patients as quickly and safely as possible."
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24.05.2017 | Universität Basel
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24.05.2017 | Empa - Eidgenössische Materialprüfungs- und Forschungsanstalt
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
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Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
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An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.
In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...
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22.05.2017 | Event News
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24.05.2017 | Life Sciences
24.05.2017 | Life Sciences
24.05.2017 | Physics and Astronomy