Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cytori Selected by Fraunhofer Society to Develop New Stem Cell-based Treatments for Stroke

17.06.2008
Cytori Therapeutics (NASDAQ: CYTX) and the Fraunhofer Institute for Cell Therapy and Immunology (IZI) form collaboration to develop adipose-derived stem cell and regenerative cell-based treatments for stroke. The Fraunhofer Society will commit $425,000 over two years in support to Cytori's already planned research and development.

The goal of the collaboration is to advance adipose-derived stem and regenerative cells into clinical trials for stroke. The underlying damage in stroke is brought about by a loss of blood flow to the brain.

Because adipose-derived stem and regenerative cells have been shown to improve tissue outcome during injury resulting from a reduction in blood flow, it is believed that these cells could represent a novel approach for reducing stroke-induced damage.

"Our interest in stroke is based on several factors," said Kai Pinkernell, M.D., head of research for Cytori. "First, stroke represents a tremendous unmet medical need, whereby vascular blockages in the brain can result in loss of brain function. Second, because stroke is brought about by a loss of blood supply, we can apply what we already know about restoring blood flow and reducing tissue damage in cardiovascular disease.

... more about:
»Cytori »Stem »adipose-derived »regenerative

Third, timing is thought to be critical in the treatment of stroke and the Celution® 800 System can make a patient's own stem and regenerative cells available in real-time."

The Fraunhofer Institute for Cell Therapy and Immunology will contribute their extensive scientific expertise in neural repair. "In combining the competencies of both partners in regenerative medicine, we will have the promising opportunity to develop a novel therapeutic strategy that might have the potential to beneficially influence functional recovery following ischemic stroke." stated Dr. Johannes Boltze, head of the Neurorepair Research Group at Fraunhofer IZI.

"For this, a step-wise experimental approach including small and large animal studies adhering to the strict STAIR-criteria for stroke therapy development will be utilized." Cytori will contribute their knowledge in adipose-derived stem and regenerative cell biology as it relates to cardiovascular conditions. At the end of the two year term, Cytori will have the opportunity to advance the work into clinical trials and through to commercialization.

"This is the third grant within the last nine months for which we have the privilege to participate," added Dr. Pinkernell. "In addition to the financial support, these grants represent significant validation from government and private organizations in the US, Japan and Germany as a testament to the global interest in regenerative medicine and how adipose-derived stem and regenerative cells may play an important role. As the pioneer in this field, we look forward to working in collaboration with organizations from around the world to bring novel therapies to patients as quickly and safely as possible."

| Fraunhofer-Gesellschaft
Further information:
http://www.fraunhofer.de

Further reports about: Cytori Stem adipose-derived regenerative

More articles from Life Sciences:

nachricht Nanoparticle Exposure Can Awaken Dormant Viruses in the Lungs
16.01.2017 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

nachricht Cholera bacteria infect more effectively with a simple twist of shape
13.01.2017 | Princeton University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

Im Focus: How to inflate a hardened concrete shell with a weight of 80 t

At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).

Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...

Im Focus: Bacterial Pac Man molecule snaps at sugar

Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.

The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...

Im Focus: Newly proposed reference datasets improve weather satellite data quality

UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration

"Traffic and weather, together on the hour!" blasts your local radio station, while your smartphone knows the weather halfway across the world. A network of...

Im Focus: Repairing defects in fiber-reinforced plastics more efficiently

Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.

Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

Nothing will happen without batteries making it happen!

05.01.2017 | Event News

 
Latest News

Multiregional brain on a chip

16.01.2017 | Power and Electrical Engineering

New technology enables 5-D imaging in live animals, humans

16.01.2017 | Information Technology

Researchers develop environmentally friendly soy air filter

16.01.2017 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>