Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

UQ researchers make West Nile vaccine breakthrough

20.05.2008
University of Queensland researchers have made a giant leap forward in the race to develop a vaccine for the potentially debilitating West Nile virus.

Associate Professor Alex Khromykh, from UQ's School of Molecular & Microbial Sciences, and colleagues have found a way to generate immune response levels comparable to a live virus vaccine, which could also help suffers of other disease such as dengue fever and Japanese encephalitis.

“What this means is that our prototype vaccine has the potential to not only be safer but just as effective as live vaccines,” Dr Khromykh said.

Dr Khromykh said West Nile virus was an emerging virus causing outbreaks of viral encephalitis in Europe and the USA.

... more about:
»Khromykh »NILE »Vaccine »encephalitis

“According to a US Center for Disease Control report, West Nile virus caused more than 27,000 cases of reported infection and more than 1000 deaths in the USA alone since its emergence in 1999,” he said.

“A vaccine is desperately needed and while a number of vaccine candidates are currently in development, none have yet been approved for human use. Following this research we hope to move on to pre-clinical and clinical trials of the vaccine.”

He said the vaccine they were developing – called pKUNdC/C – was what is known as a DNA vaccine, which is safer, purer and more stable than other vaccines prepared using traditional approaches, such as attenuated live virus vaccines.

“Live virus vaccines are usually more potent though and provoke a greater response from the immune system,” he said.

“The results we are getting show that pKUNdC/C not only has the benefits of a DNA vaccine but combines the potency of a live virus vaccine as well.

“These findings are important not only for the vaccine development against West Nile virus, but also against other highly pathogenic viruses from the same virus genus which includes dengue, tick-borne encephalitis and Japanese encephalitis viruses.”

Andrew Dunne | EurekAlert!
Further information:
http://www.uq.edu.au

Further reports about: Khromykh NILE Vaccine encephalitis

More articles from Life Sciences:

nachricht Rutgers scientists discover 'Legos of life'
23.01.2018 | Rutgers University

nachricht Researchers identify a protein that keeps metastatic breast cancer cells dormant
23.01.2018 | Institute for Research in Biomedicine (IRB Barcelona)

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Optical Nanoscope Allows Imaging of Quantum Dots

Physicists have developed a technique based on optical microscopy that can be used to create images of atoms on the nanoscale. In particular, the new method allows the imaging of quantum dots in a semiconductor chip. Together with colleagues from the University of Bochum, scientists from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute reported the findings in the journal Nature Photonics.

Microscopes allow us to see structures that are otherwise invisible to the human eye. However, conventional optical microscopes cannot be used to image...

Im Focus: Artificial agent designs quantum experiments

On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.

We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Rutgers scientists discover 'Legos of life'

23.01.2018 | Life Sciences

Seabed mining could destroy ecosystems

23.01.2018 | Earth Sciences

Transportable laser

23.01.2018 | Physics and Astronomy

VideoLinks Science & Research
Overview of more VideoLinks >>>