One is revealed in the paper’s acknowledgements, where the Alliegros thank those who helped them after Hurricane Katrina completely disrupted their laboratory at Louisiana State University (LSU) in New Orleans – and their lives – in 2005.
The second is the paper’s scientific theme: the origin of the centrosome, a component of animal cells that functions in cell division. In their paper, published in Proceedings of the National Academy of Sciences, the Alliegros give evidence that the centrosome evolved through symbiogenesis – in which previously independent organisms fuse, become mutually dependent, and over time, become a single composite organism — rather than by the evolutionary process of random, heritable mutations and natural selection.
The Alliegros moved to the MBL permanently in September 2007, after two years of attempting to forge on in a devastated New Orleans. “We realized, if we stayed there, our research program would not survive,” says Mark Alliegro, who was a professor at LSU Health Sciences Center.
The origin of the centrosome, their paper points out, has been controversial for many years. The theory of symbiogenesis as a mechanism of evolution has also stirred debate since it was introduced in the 1920s and subsequently elaborated in the 1960s by Lynn Margulis of University of Massachusetts, Amherst. Today, only two cellular components – the mitochondria and the chloroplasts – are generally accepted by evolutionary biologists as having a symbiogenetic origin. The Alliegros’ paper suggests that centrosomes are another likely candidate.
They base their argument on evidence that the centrosomes, which they obtained from the eggs of the surf clam Spisula, contain RNA that is likely a remnant of a once-independent, simpler genome that was incorporated by symbiosis.
“Most animal genes have introns, regions that are transcribed into RNA but then spliced out,” says Alliegro. “But if you look at viral genes or bacterial genes, they have little or no introns. It turns out the genes for Spisula centrosomal RNAs have few or no introns. They are a special set of RNAs that derived from intron-poor or intron-less genes, which may very well support the idea that they come from a simpler organism, like a virus or bacteria.”
The Alliegros lost their RNA library due to Katrina, and in their paper they acknowledge Gloria Giarratano of LSU Health Sciences Center, who helped them re-clone the library from DNA they recovered in the hurricane’s aftermath. They also thank Bruce and Sharon Waddell of Slidell, Louisiana, in whose home they lived after Katrina, and where “our laboratory was resurrected in part from the dining room table”; as well as Carol Burdsal and other colleagues at Tulane University, where they temporarily set up a new lab.
Robert Palazzo of Rensselaer Polytechnic Institute, a longtime visiting investigator at the MBL, is acknowledged for providing the centrosome preparation for the original RNA extractions as well as advice and encouragement. This work was supported by the National Institutes of Health as well as post-Katrina emergency recovery funds from the Society for Developmental Biology.
Diana Kenney | EurekAlert!
Researchers uncover protein-based “cancer signature”
05.12.2016 | Universität Basel
The Nagoya Protocol Creates Disadvantages for Many Countries when Applied to Microorganisms
05.12.2016 | Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water
In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
05.12.2016 | Earth Sciences
05.12.2016 | Physics and Astronomy
05.12.2016 | Life Sciences