To develop innovative drugs more efficiently is the goal of the consortium NEU ² (new-square) , which consists of the Kiel based Bionamics GmbH (Project leadership and contest applicant) the University Medical Center Hamburg-Eppendorf, Evotec AG, European ScreeningPort GmbH and the German pharma corporation Merck KGaA.
The highly experienced partners have worked out a concept to significantly accelerate the development of new drugs for neurological disorders such as Alzheimer's, Parkinson's and multiple sclerosis.The combination of excellent drug discovery and development know-how from Germany - from basic research to clinical trials, to cover the complete value chain from research to development and commercialisation - is the intention of NEU ².
This contribution is not only crucial for the improvement of the production of urgently needed drugs, but also a strengthening of the bio-pharmaceutical activities in Germany.
Dr. Timm-H. Jessen, spokesman of the consortium, emphasises the importance of the BMBF decision: “We will bridge the gap between Academia and Pharma industry. We are very pleased that an independent institution like the BMBF has confirmed our business concept and look forward to working together with our partners”.
Dr. Bernd Kirschbaum, R&D Executive of Merck Serono, adds:” BioPharma for us is an interesting approach to innovative research in networking with academia, biotech and other pharmaceutical companies. We are delighted that our consortium NEU ² with an approach coming out of our core business has made it through the first round of this contest”.
For Hamburg and Schleswig-Holstein the success is a further confirmation of its life science cluster policy.
The founding of the European ScreeningPort GmbH and the high degree of networking within the region, has supported the setup of the consortium NEU ² with the assistance of the North German Life Science Agency Norgenta.
“The fact that Merck has chosen strategic partners from North Germany shows how well progressed the cluster development in our region is”, so Dr. Kathrin Adlkofer, Managing Director of Norgenta.
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Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
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Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...
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