Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Vitamin D deficiency linked to tuberculosis

09.04.2008
Patients with active tuberculosis are more likely to be vitamin D deficient than the rest of the population. New research, presented at the annual Society for Endocrinology BES meeting in Harrogate, shows that the majority of patients with tuberculosis (TB) have low levels of vitamin D, leading to the possibility that vitamin D supplementation could reinforce current treatments or be used as a preventative measure against tuberculosis.

Researchers at the Central Middlesex Hospital in London, led by Dr Vassiliki Bravis, examined the prevalence of vitamin D deficiency in an ethnically diverse population in London who had active tuberculosis. Out of 158 patients in the study, only 11 (7%) had adequate vitamin D levels. Additionally, patients’ vitamin D levels did not vary seasonally as expected, but remained constant throughout the year.

It is currently unclear whether these findings represent a contributory factor to TB infection, with people with low vitamin D levels being more likely to contract the disease, or whether tuberculosis infection makes the body process vitamin D in an abnormal way, leading to patients becoming deficient. More research is now needed to establish whether vitamin D could provide a new line of treatment or preventative medicine against tuberculosis.

Vitamin D is manufactured by the skin after exposure to UV rays from sunlight. If you live in the UK, your vitamin D levels should fluctuate seasonally with the amount of sunlight you are exposed to, being higher in the summer and lower in the winter. Approximately 14.5% of the UK population is vitamin D deficient. However, vitamin D deficiency is more common amongst the Asian and African population, in whom TB infection is also more prevalent. Previous work indicates that vitamin D may help ward off tuberculosis as it mediates a key immune response against the bacterium that causes TB. Tuberculosis is a major global health problem, which causes over 2 million deaths every year.

Researcher Dr Vassiliki Bravis said:

“Previous research has shown that high levels of vitamin D can help inhibit tuberculosis infection. Our work shows that, within a London population, the majority of TB patients we treat are vitamin D deficient. Currently, we don’t know whether this vitamin D deficiency is a contributing factor towards them developing the disease or whether tuberculosis infection makes the body process vitamin D in an abnormal way, meaning that sufferers subsequently become vitamin D deficient. Looking towards the future, we now need to carry out trials to establish whether vitamin D supplementation could be used effectively to either prevent or help treat tuberculosis infection.”

Jennie Evans | alfa
Further information:
http://www.endocrinology.org
http://www.endocrinology.org/meetings/2008/BES2008/prog/prog.aspx

Further reports about: Population Tuberculosis deficiency deficient

More articles from Life Sciences:

nachricht Transport of molecular motors into cilia
28.03.2017 | Aarhus University

nachricht Asian dust providing key nutrients for California's giant sequoias
28.03.2017 | University of California - Riverside

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Challenging European Research Project to Develop New Tiny Microscopes

The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.

To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Researchers shoot for success with simulations of laser pulse-material interactions

29.03.2017 | Materials Sciences

Igniting a solar flare in the corona with lower-atmosphere kindling

29.03.2017 | Physics and Astronomy

As sea level rises, much of Honolulu and Waikiki vulnerable to groundwater inundation

29.03.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>