Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Ancient DNA: reconstruction of the biological history of Aldaieta necropolis

08.04.2008
A research team from the Department of Genetics, Physical Anthropology & Animal Physiology in the Faculty of Science and Technology at the Leioa campus of the University of the Basque Country (UPV/EHU), and led by Ms Concepción de la Rúa, has reconstructed the history of the evolution of human population and answered questions about history, using DNA extracted from skeleton remains.

Knowing the history of past populations and answering unresolved questions about them is highly interesting, more so when the information is obtained from the extraction of genetic material from historical remains. An example is the necropolis at Aldaieta (Araba) where some of these mysteries about these peoples have been answered – thanks to the study of their DNA.

Aldaieta brings together certain important features which make this site a prime archaeological and historical record and its conservation an important task of restoration and study. In this vein, the Department of Genetics, Physical Anthropology & Animal Physiology in the Faculty of Science and Technology at the University of the Basque Country (UPV/EHU), has undertaken a study of DNA in the necropolis at Aldaieta (Araba).

The researchers at the UPV/EHU have been studying the genetic material of ancient remains, extracted both from bones and teeth, in order to interpret the biological and social meaning of this necropolis. The study of ancient DNA is a field in which laboratory work is enormous for a number of reasons. On the one hand, in comparison with modern or current DNA, that extracted from the bones and teeth is quite degraded and is in very small quantities. As a consequence, the risk of contamination is high. This is why, at all times the results obtained have to be authenticate and it has to be demonstrated that they are not due to contamination or handling/manipulation, but have genuinely been obtained from the samples.

... more about:
»Aldaieta »DNA »Genetic »mitochondrial »necropolis »remains

The research work began with the extraction and subsequent analysis of DNA from the ancient remains (normally by the sequencing of mitochondrial DNA, a molecule inherited maternally) of each individual and in duplicate. Moreover, a third copy of the sample from each individual was sent to another laboratory and. finally, they compare all of them in order to distinguish between what is endogenous from what is the result of handling. Obviously, the results obtained from the same sample/individual have to tally in all the analyses in order to be reliable.

Interpretation of the settlement at Aldaieta

Despite the problems inherent working with ancient DNA, the methodology drawn up for the current work as well as the precautions and criteria of authentication undertaken have enabled reliable and verifiable results of the population buried at Aldaieta to be obtained.

Within the great homogeneity of the mitochondrial lines on the European continent, the genetic substrate of the population buried at Aldaieta falls within the variability of that expressed by current populations on the Cantabrian coast and Atlantic axis, thereby indicating the existence of genic flow between these human groups in ancient times.

Besides the characterisation of the mitochondrial genome, they have carried out the characterisation of the chromosome Y, using techniques focused on ancient DNA, an have shown the existence of family relationships within the necropolis, given that certain mitochondrial lines have a particular distribution, the grouping of individuals belonging to the same line having been discovered at nearby burial sites. Besides, there exists a significant differentiation gender wise, men having qualitatively and quantitatively more important funerary artefacts than women.

It is clear that the genetic analysis of skeleton remains, despite the labour-intensive work involved and the problem of authenticity of the results, has provided an essential contribution in the reconstruction of the biological history of human populations.

Irati Kortabitarte | alfa
Further information:
http://www.basqueresearch.com/berria_irakurri.asp?Berri_Kod=1690&hizk=I

Further reports about: Aldaieta DNA Genetic mitochondrial necropolis remains

More articles from Life Sciences:

nachricht Flow of cerebrospinal fluid regulates neural stem cell division
22.05.2018 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

nachricht Chemists at FAU successfully demonstrate imine hydrogenation with inexpensive main group metal
22.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

Im Focus: Computer-Designed Customized Regenerative Heart Valves

Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.

Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...

Im Focus: Light-induced superconductivity under high pressure

A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.

Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Supersonic waves may help electronics beat the heat

18.05.2018 | Power and Electrical Engineering

Keeping a Close Eye on Ice Loss

18.05.2018 | Information Technology

CrowdWater: An App for Flood Research

18.05.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>