Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Systems biology approach identifies nutrient regulation of biological clock in plants

18.03.2008
Using a systems biological analysis of genome-scale data from the model plant Arabidopsis, an international team of researchers identified that the master gene controlling the biological clock is sensitive to nutrient status.

The study will appear in the latest issue of the Proceedings of the National Academy of Sciences. This hypothesis derived from multi-network analysis of Arabidopsis genomic data, and validated experimentally, has shed light on how nutrients affect the molecular networks controlling plant growth and development in response to nutrient sensing.

The study was conducted by a team of researchers at New York University’s Center for Genomics and Systems Biology, Chile’s Pontificia Universidad Católica de Chile, Dartmouth College, and Cold Spring Harbor Labs. The study’s lead authors are Rodrigo A. Gutiérrez of the Pontificia Universidad Católica de Chile and Gloria Coruzzi of NYU’s Center for Genomics and Systems Biology. They note that the systems biology approach to uncovering nutrient regulated gene networks provides new targets for engineering traits in plants of agronomic interest such as increased nitrogen use efficiency, which could lead to reduced fertilizer cost and lowering ground water contamination by nitrates.

Scientists have previously studied how nitrogen nutrients affect gene expression as a way to understand the mechanisms that control plant growth and development. Nitrogen is an essential nutrient and a metabolic signal that is sensed and converted, resulting in the control of gene expression in plants. In addition, nitrate has been shown to serve as a signal for the control of gene expression in Arabidopsis, the first flowering plant to have its entire genome sequenced. There is existing evidence, on a gene-by-gene basis, that products of nitrogen assimilation, the amino acids glutamate (Glu) or glutamine (Gln), might serve as signals of organic nitrogen status that are sensed and in turn regulate gene expression.

... more about:
»Arabidopsis »Expression »Organic »nitrogen »nutrient

To identify genome-wide responses to such organic nitrogen signals, the researchers treated Arabidopsis seedlings with inorganic nitrogen (N) in both the presence and the absence of chemicals that inhibit the assimilation into organic N and conducted a genome-wide analysis of all genes whose expression responds to inorganic or organic forms of nitrogen. Using an integrated network model of molecular interactions for Arabidopsis--constructed by the researchers--in which approximately 7,000 genes are connected by 230,000 molecular interactions, they uncovered a sub-network of genes regulated by organic nitrogen that includes a highly connected network “hub” CCA1, which controls a plant’s biological clock, and target genes involved in nitrogen assimilation.

The findings thus provide evidence that plant nutrition, like animal nutrition, is tightly linked to circadian, or biological clock, functions as scientists have previously hypothesized. Other researchers have recently found that the central clock gene Per2 is necessary for food anticipation in mice. This study indicates that nitrogen nutrition affects CCA1, the central clock gene of plants, suggesting nutritional regulation of the biological clock occurs in plants.

James Devitt | EurekAlert!
Further information:
http://www.nyu.edu

Further reports about: Arabidopsis Expression Organic nitrogen nutrient

More articles from Life Sciences:

nachricht New application for acoustics helps estimate marine life populations
16.01.2018 | University of California - San Diego

nachricht Unexpected environmental source of methane discovered
16.01.2018 | University of Washington Health Sciences/UW Medicine

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

Im Focus: A thermometer for the oceans

Measurement of noble gases in Antarctic ice cores

The oceans are the largest global heat reservoir. As a result of man-made global warming, the temperature in the global climate system increases; around 90% of...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

White graphene makes ceramics multifunctional

16.01.2018 | Materials Sciences

Breaking bad metals with neutrons

16.01.2018 | Materials Sciences

ISFH-CalTeC is “designated test centre” for the confirmation of solar cell world records

16.01.2018 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>