In the original article, De Coppi et al. reported that amniotic fluid-derived stem cells could give rise to a variety of cell types of different lineages, including liver cells, bone-forming cells and neurons. Cattaneo and colleagues now question the evidence that these amniotic stem cells are able to produce differentiated cells with features of the neuronal lineage.
EuroStemCell coordinator Austin Smith, of the Wellcome Trust Centre for Stem Cell Research in Cambridge, says “this report emphasises the need for full and rigorous evaluation of stem cells before major claims are made. Scientists should be aware of the implications for patients' groups and wider political debates".
Stem cell biologist Ole Isacson, from Harvard Medical School, commends the editors of Nature Biotechnology for their decision to publish a challenge to high impact findings. “This [attitude]” Isacson says, “strengthens the basis of stem cell research. Discourse is an essential part of the scientific progress”. Report author Cattaneo adds, “this field remains open. We hope the discussion will continue, and look forward to hearing more about the potential of amniotic fluid-derived stem cells.”
Although the EuroStemCell project has completed its research programme, its renowned website (www.eurostemcell.org) will continue to promote discourse, discussion and debate around stem cell research when it relaunches next month.
Elena Cattaneo | alfa
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Researchers Discover New Anti-Cancer Protein
22.03.2018 | Universität Basel
An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from the Biozentrum, University of Basel, report in “Nature” that LHPP can also serve as a biomarker for the diagnosis and prognosis of liver cancer.
The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled...
In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.
Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...
Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.
They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...
A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...
For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.
In the cells of higher organisms, organelles such as the nucleus or mitochondria perform a range of complex functions necessary for life. In the networks of...
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