Published in the current edition of Viral Immunology, these findings may point the way toward developing new and more effective vaccines against diseases like influenza or HIV and enhance new developments in immunology.
The study suggests that scientists can boost the body’s resistance and fend off successive viral infections by taking components of the virus and indirectly activating specific populations of killer T cells – the body’s virus-killing cells. The virus components are introduced through a process known as “cross priming” whereby virus molecules are engulfed by immune cells to activate killer T cells.
“With this mechanism in mind, we can develop better tools to make more successful and effective vaccines,” says Sam Basta, Queen’s professor of Microbiology and Immunology, and the principal investigator of the study. The other members of the research team are master’s students Attiya Alatery and Erin Dunbar.
The researchers hope to build on their findings by next studying which immune cells do a better job of protecting the body while using this mechanism.“The answer to this question is like having the Holy Grail of immunotherapy and vaccine design within our grasp,” says Dr. Basta.
The study was funded by Natural Sciences and Engineering Research Council of Canada and the Franklin Bracken Fellowship program.
To learn more about Research at Queen's...
Communications Assistants Molly Kehoe 613.533.2877, email@example.com and Alissa Clark, 613.533.6000 ext 77513, firstname.lastname@example.org, Queen’s News & Media Services
Molly Kehoe | EurekAlert!
Atomic-level motion may drive bacteria's ability to evade immune system defenses
24.04.2017 | Indiana University
Two-dimensional melting of hard spheres experimentally unravelled after 60 years
24.04.2017 | University of Oxford
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
20.04.2017 | Event News
18.04.2017 | Event News
03.04.2017 | Event News
24.04.2017 | Physics and Astronomy
24.04.2017 | Materials Sciences
24.04.2017 | Life Sciences