Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Rapid and Reliable Pharmaceutical Production

18.06.2012
Medication can be more quickly and efficiently produced with a new version of the Sipat software.

By contrast to traditional batch methods of production, where medications are produced one step at a time, Sipat makes continuous production possible while incorporating constant quality control.



This method of production makes it possible to save up to 20 percent on costs and to cut production time from up to two months down to about ten days. Siemens will present the new version of Sipat at Achema, the world's largest chemical industry trade fair, which will be held in Frankfurt from June 18 to 22, 2012.

Manufacturing pharmaceuticals by means of batch production methods is time consuming, cost intensive, and uses a lot of energy. One batch or "charge" of products, such as tablets or capsules, moves through the production process as a unit. The raw material must be granulated, dried, pulverized, mixed, and pressed.

The process is repeatedly halted between steps so that samples can be taken. Only when it is certain that the product is completely homogenized or the active ingredient concentration has the necessary quality is the production process continued. As a result, production can take several weeks.

If the quality of the preliminary product is not up to standard, the charge is discarded. This manufacturing technique also does not make optimal use of the production facilities.

A continuous production process is less expensive, more efficient, and uses less raw materials and energy. The automation experts at Siemens have developed the Sipat software in collaboration with large pharmaceutical companies and plant manufacturers. It is the core of a continuous production system. Sipat continuously polls process data for information about moisture content, temperature, density or grain size distribution, etc.

By correlating this information, Sipat can predict the quality of any given tablet at any point in the process. If the data from the running production threatens to exceed tolerance limits, the process can be immediately adjusted. This real-time release makes it possible to achieve a production time of about ten days.

Apart from that, continuous production makes it possible to use production facilities much more efficiently. Plant manufacturers can simply integrate the newest version V4 of Sipat into their systems.

Dr. Norbert Aschenbrenner | Siemens InnovationNews
Further information:
http://www.siemens.com/innovationnews

More articles from Life Sciences:

nachricht The dense vessel network regulates formation of thrombocytes in the bone marrow
25.07.2017 | Rudolf-Virchow-Zentrum für Experimentelle Biomedizin der Universität Würzburg

nachricht Fungi that evolved to eat wood offer new biomass conversion tool
25.07.2017 | University of Massachusetts at Amherst

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Carbon Nanotubes Turn Electrical Current into Light-emitting Quasi-particles

Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers

Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...

Im Focus: Flexible proximity sensor creates smart surfaces

Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.

At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...

Im Focus: 3-D scanning with water

3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects

A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

 
Latest News

NASA mission surfs through waves in space to understand space weather

25.07.2017 | Physics and Astronomy

Strength of tectonic plates may explain shape of the Tibetan Plateau, study finds

25.07.2017 | Earth Sciences

The dense vessel network regulates formation of thrombocytes in the bone marrow

25.07.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>