Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Radical Scavengers in Red Smear Cheeses

15.12.2008
Natural carotenoid with unusual structure protects against oxidative damage

Carotenoids not only give carrots and red smear cheeses, such as Munster, Limburger, and Romadur, their characteristic red color, but they also protect organisms from oxidative stress.

A research team headed by Hans-Dieter Martin and Wilhelm Stahl at the University of Düsseldorf has now synthesized and characterized one of these carotenoids in the lab. As they report in the journal Angewandte Chemie, this compound is characterized by outstanding antioxidative and photoprotective properties.

Ranging in color from yellow to purple, carotenoids are pigments found throughout nature that act, among other things, as antioxidants. Antioxidants protect organisms from oxidative stress by capturing reactive oxygen species such as singlet oxygen and free radicals. Antioxidants are also added to foods, drugs, and plastics to prevent the oxidation of sensitive molecules.

Brevibacterium linens, bacteria used for the production of red smear cheeses, contain 3,3’-dihydorxyisorenieratene (DHIR), a carotenoid with a unique structure. Carotenoids are made of a long hydrocarbon chain with alternating single and double bonds. In addition, DHIR has phenolic groups, aromatic six-membered rings of carbon atoms with an OH group, at either end of the chain. Phenolic compounds are also known to be antioxidants; for example, they are present in the tannins in tea and wine.

By using a new synthetic route, the German research team was able to produce enough DHIR for the first comprehensive study of its properties. This revealed it to be an excellent antioxidant that beats other highly effective carotenoid antioxidants by a mile. In addition, its photoprotective properties are outstanding: DHIR protects cells from damage by UV radiation by absorbing UV light as well as capturing the free radicals produced by the radiation. These amazing antioxidative and photoprotective properties seem to stem from synergistic cooperation of the carotenoid and phenolic structural elements of DHIR.

When scavenging free radicals, in some cases both of the phenolic groups are first oxidized to quinoid groups. The resulting quinoid carotenoid, which the researchers were also able to synthesize and characterize, is itself also a very strong antioxidant. Interestingly, it is blue and thus broadens the color palette attainable with carotenoids.

Whether DHIR and its quinoid oxidation product can be used industrially as food and feed colorants, cosmetics, or antioxidants, is currently under investigation. These compounds may also be useful for the prevention of degenerative diseases related to free-radical damage, such as macular degeneration.

Author: Hans-Dieter Martin, Heinrich-Heine-Universität Düsseldorf (Germany), http://www.chemie.uni-duesseldorf.de/Faecher/Organische_Chemie/OC1/Martin

Title: 3,3’-Dihydroxyisorenieratene, a Natural Carotenoid with Superior Antioxidant and Photoprotective Properties

Angewandte Chemie International Edition 2009, 48, No. 2, doi: 10.1002/anie.200803668

Hans-Dieter Martin | Angewandte Chemie
Further information:
http://pressroom.angewandte.org
http://www.chemie.uni-duesseldorf.de/Faecher/Organische_Chemie/OC1/Martin

More articles from Life Sciences:

nachricht Nanoparticle Exposure Can Awaken Dormant Viruses in the Lungs
16.01.2017 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

nachricht Cholera bacteria infect more effectively with a simple twist of shape
13.01.2017 | Princeton University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

Im Focus: How to inflate a hardened concrete shell with a weight of 80 t

At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).

Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...

Im Focus: Bacterial Pac Man molecule snaps at sugar

Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.

The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...

Im Focus: Newly proposed reference datasets improve weather satellite data quality

UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration

"Traffic and weather, together on the hour!" blasts your local radio station, while your smartphone knows the weather halfway across the world. A network of...

Im Focus: Repairing defects in fiber-reinforced plastics more efficiently

Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.

Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

Nothing will happen without batteries making it happen!

05.01.2017 | Event News

 
Latest News

Multiregional brain on a chip

16.01.2017 | Power and Electrical Engineering

New technology enables 5-D imaging in live animals, humans

16.01.2017 | Information Technology

Researchers develop environmentally friendly soy air filter

16.01.2017 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>