Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Putting the spotlight on membranous nephropathy

The Halpin Foundation and the American Society of Nephrology (ASN) proudly highlight the research advances in membranous nephropathy made possible by The Halpin Foundation-ASN Research Grant, created to help young faculty develop independent research careers. This award provides recipients transition funding toward successful application for an NIH RO1 grant.

Elena Torban, PhD (McGill University Faculty of Medicine), the 2008 recipient of The Halpin Foundation-ASN Research Grant, recently explained, "The generous financial two-year support provided by The Halpin Foundation has enabled us to conduct a successful experimental program demonstrating for the first time that podocyte architecture is indeed regulated by the PCP pathway. We also showed that the podocyte-specific protein, nephrin, is linked to proteins of the PCP network. This finding establishes a mechanism whereby the PCP pathway regulates nephrin-dependent organization of foot processes."

The 2009 recipient of The Halpin Foundation Laurence H. Beck, Jr., MD, PhD wrote of the grant, "The funding provided by the Halpin Foundation has been instrumental in allowing my research to take root and grow. The research award has permitted me to spend the majority of these two years in the laboratory, performing experiments and helping to train young scientists and fellows conduct similar lines of inquiry. The fruits of this research should soon allow me to successfully apply for individual federal funding. Their ongoing interactions with leaders in this field on a national and international level have been enormously helpful for me in terms of forming productive collaborations to move this research forward. I will always be grateful for this support at such a critical time in the career of a young physician-scientist."

Dr. Beck and several colleagues will also participate in a Clinical Nephrology Conference (CNC) during Renal Week entitled, "Membranous Nephropathy" on Friday, November 19 from 10:30 am – 12:30 pm in Korbel 2A/3A of the Colorado Convention Center in Denver, CO. The session, "The Human Membranous Antibody: Mechanism and Monitoring" is a way to highlight research advances and stimulate investigations regarding membranous nephropathy.

The Halpin Foundation has dedicated itself to the study of membranous nephropathy since 1989, after the Halpins' 14-year-old son was diagnosed with this rare disorder. To advance research of the disorder and its symptoms, including loss of protein in the urine and a progressive decline in renal function, The Halpin Foundation partnered with the American Society of Nephrology (ASN) to promote research relevant to membranous nephropathy in 2004.

The foundation is committed to advancing the medical community's understanding of membranous nephropathy, including whether there is a hereditary predisposition to the disease. In addition, The Halpin Foundation works to raise awareness of membranous nephropathy in the scientific and lay communities.

"We are grateful to The Halpin Foundation for helping us fund new investigators interested in studying this disease to answer the many unanswered questions surrounding membranous nephropathy and nephrotic syndrome, said ASN's President, Sharon Anderson, MD, FASN.

Joan Halpin, President of the Halpin Foundation, is hopeful this program will "attract a diverse audience that will be encouraged to devote time and intellect to the consideration of the pathogenesis and therapy for this disorder."

ASN Renal Week 2010, the largest nephrology meeting of its kind, will provide a forum for 13,000 professionals to discuss the latest findings in renal research and engage in educational sessions related to advances in the care of patients with kidney and related disorders. Renal Week 2010 will take place November 16 – November 21 at the Colorado Convention Center in Denver, CO.

The content of this article does not reflect the views or opinions of The American Society of Nephrology (ASN). Responsibility for the information and views expressed therein lies entirely with the author(s). ASN does not offer medical advice. All content in ASN publications is for informational purposes only, and is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This content should not be used during a medical emergency or for the diagnosis or treatment of any medical condition. Please consult your doctor or other qualified health care provider if you have any questions about a medical condition, or before taking any drug, changing your diet or commencing or discontinuing any course of treatment. Do not ignore or delay obtaining professional medical advice because of information accessed through ASN. Call 911 or your doctor for all medical emergencies.

Founded in 1966, the American Society of Nephrology (ASN) is the world's largest professional society devoted to the study of kidney disease. Comprised of 11,000 physicians and scientists, ASN continues to promote expert patient care, to advance medical research, and to educate the renal community. ASN also informs policymakers about issues of importance to kidney doctors and their patients. ASN funds research, and through its world-renowned meetings and first-class publications, disseminates information and educational tools that empower physicians.

Shari Leventhal | EurekAlert!
Further information:

Further reports about: ASN Colorado river Foundation Foundation-ASN Halpin Nephrology PCP membranous nephropathy

More articles from Life Sciences:

nachricht Don't Give the Slightest Chance to Toxic Elements in Medicinal Products
23.03.2018 | Physikalisch-Technische Bundesanstalt (PTB)

nachricht North and South Cooperation to Combat Tuberculosis
22.03.2018 | Universität Zürich

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Space observation with radar to secure Germany's space infrastructure

Satellites in near-Earth orbit are at risk due to the steady increase in space debris. But their mission in the areas of telecommunications, navigation or weather forecasts is essential for society. Fraunhofer FHR therefore develops radar-based systems which allow the detection, tracking and cataloging of even the smallest particles of debris. Satellite operators who have access to our data are in a better position to plan evasive maneuvers and prevent destructive collisions. From April, 25-29 2018, Fraunhofer FHR and its partners will exhibit the complementary radar systems TIRA and GESTRA as well as the latest radar techniques for space observation across three stands at the ILA Berlin.

The "traffic situation" in space is very tense: the Earth is currently being orbited not only by countless satellites but also by a large volume of space...

Im Focus: Researchers Discover New Anti-Cancer Protein

An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from the Biozentrum, University of Basel, report in “Nature” that LHPP can also serve as a biomarker for the diagnosis and prognosis of liver cancer.

The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled...

Im Focus: Researchers at Fraunhofer monitor re-entry of Chinese space station Tiangong-1

In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.

Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...

Im Focus: Alliance „OLED Licht Forum“ – Key partner for OLED lighting solutions

Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.

They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...

Im Focus: Mars' oceans formed early, possibly aided by massive volcanic eruptions

Oceans formed before Tharsis and evolved together, shaping climate history of Mars

A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...

All Focus news of the innovation-report >>>



Industry & Economy
Event News

New solar solutions for sustainable buildings and cities

23.03.2018 | Event News

Virtual reality conference comes to Reutlingen

19.03.2018 | Event News

Ultrafast Wireless and Chip Design at the DATE Conference in Dresden

16.03.2018 | Event News

Latest News

For graphite pellets, just add elbow grease

23.03.2018 | Materials Sciences

Unique communication strategy discovered in stem cell pathway controlling plant growth

23.03.2018 | Agricultural and Forestry Science

Sharpening the X-ray view of the nanocosm

23.03.2018 | Physics and Astronomy

Science & Research
Overview of more VideoLinks >>>