Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Protein May Provide the Key to Arresting Development of Diabetes

04.09.2014

The STK25 protein contributes to cell growth. Researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, have discovered that the protein also affects metabolism, demonstrating that elevated levels accelerate the progress of diabetes in mice.

Researchers at Sahlgrenska Academy, University of Gothenburg have discovered a protein that may open the door to a new method of treating type 2 diabetes and other diseases caused by metabolic disorders.

Current methods not effective

Emmelie Cansby’s doctoral thesis has shown that the reduction of STK25 protein in cell cultures improves metabolism. The studies also found that mice that have elevated STK25 levels and are fed a high-fat diet are more likely to develop symptoms of diabetes.

”Current methods for treating diabetes are not effective enough,” Emmelie Cansby says. “Furthermore, they have various adverse effects, including hypoglycemia, weight gain, edema and gastrointestinal problems. New, supplementary drugs for type 2 diabetes are badly needed.”

Potential treatment

Her thesis concludes that the STK25 protein offers the potential for an entirely new way of treating diabetes.

“Future treatment of diabetes and other metabolic disorders will hopefully include drugs that inhibit the action of STK25,” she says.

Emmelie Cansby will present her thesis, Regulation of metabolism and inflammation by two protein kinases – AMPK and STK25, on September 5.

Link to thesis: http://hdl.handle.net/2077/35938

Contact:
Emmelie Cansby, Doctoral Student, Sahlgrenska Academy, University of Gothenburg
emmelie.cansby@gu.se

Supervisor Margit Mahlapuu, Associate Professor, +46 706 310109, margit.mahlapuu@gu.se

Weitere Informationen:

http://sahlgrenska.gu.se/english/news_and_events/news/News_Detail/protein-may-pr...

Henrik Axlid | idw - Informationsdienst Wissenschaft

Further reports about: Diabetes Gothenburg Protein Sahlgrenska disorders drugs metabolic metabolism

More articles from Life Sciences:

nachricht The herbivore dilemma: How corn plants fights off simultaneous attacks
09.02.2016 | Boyce Thompson Institute for Plant Research

nachricht Shedding Light on Bacteria
09.02.2016 | Albert-Ludwigs-Universität Freiburg im Breisgau

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New study: How stable is the West Antarctic Ice Sheet?

Exceeding critical temperature limits in the Southern Ocean may cause the collapse of ice sheets and a sharp rise in sea levels

A future warming of the Southern Ocean caused by rising greenhouse gas concentrations in the atmosphere may severely disrupt the stability of the West...

Im Focus: Superconductivity: footballs with no resistance

Indications of light-induced lossless electricity transmission in fullerenes contribute to the search for superconducting materials for practical applications.

Superconductors have long been confined to niche applications, due to the fact that the highest temperature at which even the best of these materials becomes...

Im Focus: Wbp2 is a novel deafness gene

Researchers at King’s College London and the Wellcome Trust Sanger Institute in the United Kingdom have for the first time demonstrated a direct link between the Wbp2 gene and progressive hearing loss. The scientists report that the loss of Wbp2 expression leads to progressive high-frequency hearing loss in mouse as well as in two clinical cases of children with deafness with no other obvious features. The results are published in EMBO Molecular Medicine.

The scientists have shown that hearing impairment is linked to hormonal signalling rather than to hair cell degeneration. Wbp2 is known as a transcriptional...

Im Focus: From allergens to anodes: Pollen derived battery electrodes

Pollens, the bane of allergy sufferers, could represent a boon for battery makers: Recent research has suggested their potential use as anodes in lithium-ion batteries.

"Our findings have demonstrated that renewable pollens could produce carbon architectures for anode applications in energy storage devices," said Vilas Pol, an...

Im Focus: Automated driving: Steering without limits

OmniSteer project to increase automobiles’ urban maneuverability begins with a € 3.4 million budget

Automobiles increase the mobility of their users. However, their maneuverability is pushed to the limit by cramped inner city conditions. Those who need to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Travel grants available: Meet the world’s most proficient mathematicians and computer scientists

09.02.2016 | Event News

AKL’16: Experience Laser Technology Live in Europe´s Largest Laser Application Center!

02.02.2016 | Event News

From intelligent knee braces to anti-theft backpacks

26.01.2016 | Event News

 
Latest News

Travel grants available: Meet the world’s most proficient mathematicians and computer scientists

09.02.2016 | Event News

Body temperature triggers newly developed polymer to change shape

09.02.2016 | Materials Sciences

Using renewable energy in heating networks more efficiently

09.02.2016 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>