Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Protection for stressed-out bacteria identified

10.10.2008
An international team of researchers is a step closer to understanding the spread of deadly diseases such as listeriosis, after observing for the first time how bacteria respond to stress.

The research, published in the October issue of the prestigious international journal Science, details how a huge molecule called a stressosome protects bacterial cells from external stress and danger.

Scientists from the University of Newcastle in Australia, and Newcastle University and Imperial College in the United Kingdom, collaborated on the discovery.

Associate Professor Peter Lewis from the Faculty of Science and Information Technology at the University of Newcastle in Australia said until now, researchers had not fully understood how bacteria responded to stress and potential danger.

"It is important to understand the changes that occur when bacteria are under stress as this is the point at which they are likely to become most infectious.

"The protein molecules that make up the stressosome are found in a very wide range of bacteria. Some of these bacteria cause diseases such as listeriosis that has a 30 per cent mortality rate, and melioidosis that has a mortality rate as high as 90 per cent and is a significant health problem in northern Australia and south-east Asia.

"With bacteria becoming increasingly resistant to antibiotics, understanding how the stress response is controlled could lead to the development of drugs that help prevent bacterial infection from occurring."

Lead author of the Science paper, Professor Rick Lewis from Newcastle University in the United Kingdom, said the team used groundbreaking techniques to observe the stressosomes. Electron microscopy techniques were developed by Professor Marin van Heel of Imperial College and Associate Professor Peter Lewis developed the fluorescence microscopy imaging techniques.

"We knew that when bacteria were stressed, a warning signal would be sent from the surface to the inside of the cell. The stressosome would then respond by triggering new proteins in the cell to react to the stress.

"Our latest work has revealed the structure and number of stressosomes per cell. This has helped us understand how quickly the stressosomes respond to external stresses and prepare the cell to adapt to changes in its environment and ensure its survival."

Blythe Hamilton | EurekAlert!
Further information:
http://www.newcastle.edu.au

More articles from Life Sciences:

nachricht Water world
20.11.2017 | Washington University in St. Louis

nachricht Carefully crafted light pulses control neuron activity
20.11.2017 | University of Illinois at Urbana-Champaign

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

Im Focus: Wrinkles give heat a jolt in pillared graphene

Rice University researchers test 3-D carbon nanostructures' thermal transport abilities

Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

Antarctic landscape insights keep ice loss forecasts on the radar

20.11.2017 | Earth Sciences

Filling the gap: High-latitude volcanic eruptions also have global impact

20.11.2017 | Earth Sciences

Water world

20.11.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>