Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

PolyU scientist finds novel use of African mushroom in cancer research

07.02.2012
A young scientist from PolyU's Food Safety and Technology Research Centre has successfully prepared highly stable selenium nanoparticles by using the polysaccharide-protein complex extracted from the African Tiger Milk mushroom.

A young scientist from The Hong Kong Polytechnic University (PolyU)'s Food Safety and Technology Research Centre (FSTRC) has successfully prepared highly stable selenium nanoparticles by using the polysaccharide-protein complex extracted from the African Tiger Milk mushroom.

The preliminary study discovered that these stabilized selenium nanoparticles can significantly inhibit the growth of breast cancer cells by apoptosis.

With this breakthrough, FSTRC Associate Director Dr Wong Ka-hing, who is also an Assistant Professor of PolyU's Department of Applied Biology and Chemical Technology, has won the Young Investigator Award in the 2011 International Conference of Food Factors (ICoFF 2011) with the theme "Food for Wellbeing-from Function to Processing".

Selenium is a trace element which is essential for human health. The study of selenium nanoparticles has become a hot topic because of their excellent bio-availability, low toxicity and strong anti-cancer activity. However, nanoparticles would easily stick together, and their special properties would be lost once the aggregates exceed nano-size. That is why scientists around the world have been exploring ways to stabilize the nanoparticles.

Dr Wong's award-winning study is entitled "Preparation of Highly Stable Selenium Nanoparticles with Anti-Cancer Activity under a Food Grade Redox System" – which means the ultimate products could be consumed as functional food or health products. The study is the first of its kind in terms of preparing highly stable selenium nanoparticles with the use of mushroom polysaccharide-protein complexes as the stabilizers. Apart from its potential as functional foods, the finding has also provided insights on using these novel nanoparticles as new drug for cancer chemoprevention.

In the next stage of cancer research, Dr Wong would evaluate the anti-cancer activity of those stabilized selenium nanoparticles on small animals, and elucidate the underlying mechanism of their growth inhibition effects on the breast cancer cells.

The polysaccharide-protein complex currently in use is extracted from the sclerotium of Tiger Milk mushroom. Dr Wong would also further investigate whether its other developmental stages (e.g. fruiting body) could be used for this cancer research. PolyU has partnered with a mushroom farm to produce Tiger Milk mushrooms and support further research.

The ICoFF at which Dr Wong received his award was organized by the Association of Agricultural Chemists (AOAC) International (Taiwan Section). This year more than 1,300 participants from 30 countries have attended the event, during which numerous international renowned scholars and experts were invited to give lectures on health promotion, diseases prevention and other health issues related to food.
Press contact: Dr Wong Ka-hing
Associate Director, Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology

Tel: (852) 3400 8864
Email: bckhwong@polyu.edu.hk

Regina Yu | Research asia research news
Further information:
http://www.polyu.edu.hk

More articles from Life Sciences:

nachricht Symbiotic bacteria: from hitchhiker to beetle bodyguard
28.04.2017 | Johannes Gutenberg-Universität Mainz

nachricht Nose2Brain – Better Therapy for Multiple Sclerosis
28.04.2017 | Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik IGB

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Fighting drug resistant tuberculosis – InfectoGnostics meets MYCO-NET² partners in Peru

28.04.2017 | Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

 
Latest News

Wireless power can drive tiny electronic devices in the GI tract

28.04.2017 | Medical Engineering

Ice cave in Transylvania yields window into region's past

28.04.2017 | Earth Sciences

Nose2Brain – Better Therapy for Multiple Sclerosis

28.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>