Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Placing Active Agents in the Body with "Mini-Containers"

16.11.2009
New Research Collaboration at Jena University funded with Euro 1.25 million

Jena scientists from different disciplines founded a new network in order to utilize so-called nanocontainers for applications in the biomedical field ("NanoConSens"). The research collaboration is now being funded by the State of Thuringia for the next 3 years with EUR 1.25 million within the framework of the "ProExzellenz Initiative".

"We aim at building up and optimizing various nanocontainers in such way that they - as intelligent transport vehicles - release active agents in the right dose at the right time at the right place in the human body", Prof. Dr. Ulrich S. Schubert from the University in Jena describes the direction of the project. "With that, high-impact medicine which is not blood soluble", explains the initiative's coordinator, "can be selectively transported to its destination without side effects. We are striving to enclose, for instance, antibiotics or even complex molecules like siRNA."

Such different substances require transport vehicles that are individually tailored to the special type of molecule. Moreover, they have to be provided with molecules navigating on their surface, like for example sugars or peptides. The new collaboration is, among other things, using combinations of novel concepts for building up star-shaped polymers, employing cationic polymers, varying the size of the nanocontainers and utilizing state-of-the-art methods of synthesis (like the so-called "click chemistry"). Furthermore, modified nanocontainers can be employed as sensors for the investigation of living cells - for example to determine ionic concentration, temperature or pH value.

The eight funded interdisciplinary subprojects unite partners from such disciplines as chemistry, pharmacy, medicine and biology from the Friedrich Schiller University Jena and the Leibniz Institute for Natural Product Research and Infection Biology - "Hans-Knöll-Institute" (HKI). The entire project helps strengthen the research profile of the Friedrich Schiller University Jena and its research focus on "Innovative Materials and Technologies" (www.materials.uni-jena.de).

Contact:
Prof. Dr. Ulrich S. Schubert
Institute of Organic Chemistry and Macromolecular Chemistry at Jena University
Humboldtstr. 10
D-07743 Jena
Tel.: +49-3641-948201
Email: info[at]schubert-group.de

Axel Burchardt | idw
Further information:
http://www.uni-jena.de

More articles from Life Sciences:

nachricht A novel socio-ecological approach helps identifying suitable wolf habitats
17.02.2017 | Universität Zürich

nachricht New, ultra-flexible probes form reliable, scar-free integration with the brain
16.02.2017 | University of Texas at Austin

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Switched-on DNA

20.02.2017 | Materials Sciences

Second cause of hidden hearing loss identified

20.02.2017 | Health and Medicine

Prospect for more effective treatment of nerve pain

20.02.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>