Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Placing Active Agents in the Body with "Mini-Containers"

16.11.2009
New Research Collaboration at Jena University funded with Euro 1.25 million

Jena scientists from different disciplines founded a new network in order to utilize so-called nanocontainers for applications in the biomedical field ("NanoConSens"). The research collaboration is now being funded by the State of Thuringia for the next 3 years with EUR 1.25 million within the framework of the "ProExzellenz Initiative".

"We aim at building up and optimizing various nanocontainers in such way that they - as intelligent transport vehicles - release active agents in the right dose at the right time at the right place in the human body", Prof. Dr. Ulrich S. Schubert from the University in Jena describes the direction of the project. "With that, high-impact medicine which is not blood soluble", explains the initiative's coordinator, "can be selectively transported to its destination without side effects. We are striving to enclose, for instance, antibiotics or even complex molecules like siRNA."

Such different substances require transport vehicles that are individually tailored to the special type of molecule. Moreover, they have to be provided with molecules navigating on their surface, like for example sugars or peptides. The new collaboration is, among other things, using combinations of novel concepts for building up star-shaped polymers, employing cationic polymers, varying the size of the nanocontainers and utilizing state-of-the-art methods of synthesis (like the so-called "click chemistry"). Furthermore, modified nanocontainers can be employed as sensors for the investigation of living cells - for example to determine ionic concentration, temperature or pH value.

The eight funded interdisciplinary subprojects unite partners from such disciplines as chemistry, pharmacy, medicine and biology from the Friedrich Schiller University Jena and the Leibniz Institute for Natural Product Research and Infection Biology - "Hans-Knöll-Institute" (HKI). The entire project helps strengthen the research profile of the Friedrich Schiller University Jena and its research focus on "Innovative Materials and Technologies" (www.materials.uni-jena.de).

Contact:
Prof. Dr. Ulrich S. Schubert
Institute of Organic Chemistry and Macromolecular Chemistry at Jena University
Humboldtstr. 10
D-07743 Jena
Tel.: +49-3641-948201
Email: info[at]schubert-group.de

Axel Burchardt | idw
Further information:
http://www.uni-jena.de

More articles from Life Sciences:

nachricht Ambush in a petri dish
24.11.2017 | Friedrich-Schiller-Universität Jena

nachricht Meadows beat out shrubs when it comes to storing carbon
23.11.2017 | Norwegian University of Science and Technology

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New proton record: Researchers measure magnetic moment with greatest possible precision

High-precision measurement of the g-factor eleven times more precise than before / Results indicate a strong similarity between protons and antiprotons

The magnetic moment of an individual proton is inconceivably small, but can still be quantified. The basis for undertaking this measurement was laid over ten...

Im Focus: Frictional Heat Powers Hydrothermal Activity on Enceladus

Computer simulation shows how the icy moon heats water in a porous rock core

Heat from the friction of rocks caused by tidal forces could be the “engine” for the hydrothermal activity on Saturn's moon Enceladus. This presupposes that...

Im Focus: Nanoparticles help with malaria diagnosis – new rapid test in development

The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.

Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

IceCube experiment finds Earth can block high-energy particles from nuclear reactions

24.11.2017 | Physics and Astronomy

A 'half-hearted' solution to one-sided heart failure

24.11.2017 | Health and Medicine

Heidelberg Researchers Study Unique Underwater Stalactites

24.11.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>