In a literature study the ESHRE Task Force on Ethics and Law summarised the negative effects of obesity, smoking and drinking on the natural reproductive potential of patients, on IVF results, pregnancy complications and outcomes and finally on the health of the future child. The paper is published online today (19 January 2010) in Europe’s leading reproductive medicine journal Human Reproduction (1). The group made five recommendations.
1) In view of the risks for the future child, fertility doctors should refuse treatment to women used to more than moderate drinking and who are not willing or able to minimize their alcohol consumption.
2) Treating women with severe or morbid obesity required special justification. The available data suggested that weight loss would incur in a positive reproductive effect, although more data was needed to establish whether assisted reproduction should be made conditional upon prior life-style changes for obese and smoking females.
3) Assisted reproduction should only be conditional upon life style changes, if there was strong evidence that without behavioural modifications there was a risk of serious harm to the child or that the treatment became disproportional in terms of cost-effectiveness or obstetric risks.
4) When making assisted reproduction conditional upon life style modifications, fertility doctors should help patients to achieve the necessary results.5) More data on obesity, smoking and alcohol consumption as well as other life style factors were necessary to assess reproductive effects. Fertility doctors should continue research in this area.
ESHRE acknowledged that this was a complex issue due to personal, patient, professional and societal responsibilities and also in terms of what these responsibilities meant with regard to safety of mother and child and fair and equitable access to treatment. The respect for patient autonomy needed to be balanced with the moral weight of the interests of society and the future child.Obesity
Human Reproduction is a monthly journal of the European Society of Human Reproduction and Embryology (ESHRE), and is published by Oxford Journals, a division of Oxford University Press. Please acknowledge Human Reproduction as a source in any articles.
ESHRE was founded in 1985 with the mission to promote the understanding of reproductive science and medicine. It does this through facilitating research and subsequent dissemination of research findings in human reproduction and embryology to the general public, scientists, clinicians, patient associations, politicians and key policy makers across Europe. Please visit: www.eshre.eu.
The ESHRE Task Force on Ethics & Law is part of the Special Interest Group (SIG) Ethics & Law which proposes ethical guidelines on specific moral issues in the practice of ART.For more information please contact:
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