Johannes Gutenberg University Mainz and Institute of Molecular Biology collaborate in three-year research project funded by the Ministry of Science
Johannes Gutenberg University Mainz (JGU) has received EUR 900,000 for three years to investigate, jointly with the Institute of Molecular Biology (IMB), how gene regulation affects evolution and development.
The ambitious new research initiative GeneRED, or Gene Regulation in Evolution and Development, is jointly run by IMB and JGU's Faculty of Biology, funded by the Ministry of Education, Science, Continuing Education, and Culture of Rhineland-Palatinate.
Its overarching goal is to gain insight into how epigenetics, i.e., the regulation of genes by elements outside the classical DNA code, can influence the development of organisms, both in the short term (growth and aging) and the long term (evolutionary adaptation).
The initiative aims to significantly strengthen research into gene regulation on the campus of Johannes Gutenberg University Mainz. To achieve this, it will fund six PhD positions at JGU's Faculty of Biology over three years (2014-2016). The questions these students are studying are:
* How did division of labor evolve in social insects like ants, and which genes are involved?
* How does the NURF complex help maintain neural stem cell identity in fruit flies?
* What are the targets of the NG2 protein in glial cell development and tumors?
* How do ciliary proteins affect DNA damage response and gene regulation in Usher syndrome?
* What are the roles of genetic regulatory elements in the modern human adaptation to an agriculturalist diet and predisposition to metabolic syndrome?
* Which epigenetic factors are involved in creating body size memory in fruit flies?
The participating PhD students will be fully integrated into the International PhD Program on "Dynamics of Gene Regulation, Epigenetics and DNA Damage Response," a joint program coordinated by IMB with groups from IMB, JGU, the Mainz University Medical Center, and the Max Planck Institute for Polymer Research.
The initiative will also help expand access to modern proteomics technologies for scientists at JGU and IMB. With proteomics becoming a key methodology in modern biomedical research, the support provided through this initiative will be crucial in ensuring that research in Mainz is internationally competitive.
The chairs of the GeneRED project are Hans Zischler, Dean of the Faculty of Biology at JGU, and Christof Niehrs, Founding and Executive Director of IMB. The General Manager of GeneRED is Ralf Dahm, IMB's Director of Scientific Management.
About the Institute for Molecular Biology gGmbH
The Institute of Molecular Biology gGmbH (IMB) is a center of excellence in the life sciences that was established in 2011. Research at IMB concentrates on three cutting-edge areas: epigenetics, developmental biology, and DNA repair. The institute is a prime example of a successful collaboration between public authorities and a private foundation. The Boehringer Ingelheim Foundation has dedicated EUR 100 million for a period of 10 years to cover the operating costs for research at IMB, while the state of Rhineland-Palatinate provided approximately EUR 50 million for the construction of a state-of-the-art building. For more information about IMB, please visit www.imb.de
About the Boehringer Ingelheim Foundation
The Boehringer Ingelheim Foundation is an independent, non-profit organization committed to the promotion of the medical, biological, chemical, and pharmaceutical sciences. It was established in 1977 by Hubertus Liebrecht (1931-1991), a member of the shareholder family of the company Boehringer Ingelheim. Through its PLUS 3 Perspectives Program and Exploration Grants, the foundation supports independent group leaders; it also endows the internationally renowned Heinrich Wieland Prize as well as awards for up-and-coming scientists. The foundation has granted EUR 100 million over a period of ten years to finance the scientific activities of the Institute of Molecular Biology (IMB).
For more information about the foundation and its programs, please visit www.boehringer-ingelheim-stiftung.de
Press contact for further information
Dr Ralf Dahm, Director of Scientific Management
Institute of Molecular Biology gGmbH (IMB)
Ackermannweg 4, 55128 Mainz, Germany
phone: +49 6131 39-21455
fax: +49 6131 39-21421
http://www.uni-mainz.de/presse/17179_ENG_HTML.php - press release ;
https://www.imb-mainz.de/research/initiatives/GeneRED/ - Gene Regulation in Evolution and Development (GeneRED)
Petra Giegerich | idw - Informationsdienst Wissenschaft
The irresistible fragrance of dying vinegar flies
16.08.2017 | Max-Planck-Institut für chemische Ökologie
How protein islands form
15.08.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
Researchers from the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science, the Italian Space Agency (ASI), and the Instituto Geofisico--Escuela Politecnica Nacional (IGEPN) of Ecuador, showed an increasing volcanic danger on Cotopaxi in Ecuador using a powerful technique known as Interferometric Synthetic Aperture Radar (InSAR).
The Andes region in which Cotopaxi volcano is located is known to contain some of the world's most serious volcanic hazard. A mid- to large-size eruption has...
16.08.2017 | Event News
04.08.2017 | Event News
26.07.2017 | Event News
16.08.2017 | Physics and Astronomy
16.08.2017 | Materials Sciences
16.08.2017 | Interdisciplinary Research