Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New research initiative investigates gene regulation in evolution and development

03.04.2014

Johannes Gutenberg University Mainz and Institute of Molecular Biology collaborate in three-year research project funded by the Ministry of Science

Johannes Gutenberg University Mainz (JGU) has received EUR 900,000 for three years to investigate, jointly with the Institute of Molecular Biology (IMB), how gene regulation affects evolution and development.

The ambitious new research initiative GeneRED, or Gene Regulation in Evolution and Development, is jointly run by IMB and JGU's Faculty of Biology, funded by the Ministry of Education, Science, Continuing Education, and Culture of Rhineland-Palatinate.

Its overarching goal is to gain insight into how epigenetics, i.e., the regulation of genes by elements outside the classical DNA code, can influence the development of organisms, both in the short term (growth and aging) and the long term (evolutionary adaptation).

... more about:
»Biology »Boehringer »DNA »Development »IMB »JGU »Molecular »flies »genes

The initiative aims to significantly strengthen research into gene regulation on the campus of Johannes Gutenberg University Mainz. To achieve this, it will fund six PhD positions at JGU's Faculty of Biology over three years (2014-2016). The questions these students are studying are:

* How did division of labor evolve in social insects like ants, and which genes are involved?
* How does the NURF complex help maintain neural stem cell identity in fruit flies?
* What are the targets of the NG2 protein in glial cell development and tumors?
* How do ciliary proteins affect DNA damage response and gene regulation in Usher syndrome?
* What are the roles of genetic regulatory elements in the modern human adaptation to an agriculturalist diet and predisposition to metabolic syndrome?
* Which epigenetic factors are involved in creating body size memory in fruit flies?

The participating PhD students will be fully integrated into the International PhD Program on "Dynamics of Gene Regulation, Epigenetics and DNA Damage Response," a joint program coordinated by IMB with groups from IMB, JGU, the Mainz University Medical Center, and the Max Planck Institute for Polymer Research.

The initiative will also help expand access to modern proteomics technologies for scientists at JGU and IMB. With proteomics becoming a key methodology in modern biomedical research, the support provided through this initiative will be crucial in ensuring that research in Mainz is internationally competitive.

The chairs of the GeneRED project are Hans Zischler, Dean of the Faculty of Biology at JGU, and Christof Niehrs, Founding and Executive Director of IMB. The General Manager of GeneRED is Ralf Dahm, IMB's Director of Scientific Management.

About the Institute for Molecular Biology gGmbH
The Institute of Molecular Biology gGmbH (IMB) is a center of excellence in the life sciences that was established in 2011. Research at IMB concentrates on three cutting-edge areas: epigenetics, developmental biology, and DNA repair. The institute is a prime example of a successful collaboration between public authorities and a private foundation. The Boehringer Ingelheim Foundation has dedicated EUR 100 million for a period of 10 years to cover the operating costs for research at IMB, while the state of Rhineland-Palatinate provided approximately EUR 50 million for the construction of a state-of-the-art building. For more information about IMB, please visit www.imb.de

About the Boehringer Ingelheim Foundation
The Boehringer Ingelheim Foundation is an independent, non-profit organization committed to the promotion of the medical, biological, chemical, and pharmaceutical sciences. It was established in 1977 by Hubertus Liebrecht (1931-1991), a member of the shareholder family of the company Boehringer Ingelheim. Through its PLUS 3 Perspectives Program and Exploration Grants, the foundation supports independent group leaders; it also endows the internationally renowned Heinrich Wieland Prize as well as awards for up-and-coming scientists. The foundation has granted EUR 100 million over a period of ten years to finance the scientific activities of the Institute of Molecular Biology (IMB).
For more information about the foundation and its programs, please visit www.boehringer-ingelheim-stiftung.de

Press contact for further information
Dr Ralf Dahm, Director of Scientific Management
Institute of Molecular Biology gGmbH (IMB)
Ackermannweg 4, 55128 Mainz, Germany
phone: +49 6131 39-21455
fax: +49 6131 39-21421
e-mail: press@imb.de

Weitere Informationen:

http://www.uni-mainz.de/presse/17179_ENG_HTML.php - press release ;
https://www.imb-mainz.de/research/initiatives/GeneRED/ - Gene Regulation in Evolution and Development (GeneRED)

Petra Giegerich | idw - Informationsdienst Wissenschaft

Further reports about: Biology Boehringer DNA Development IMB JGU Molecular flies genes

More articles from Life Sciences:

nachricht Shark Tagged by NSU’s Guy Harvey Research Institute Is Apparently Enjoying Time in Warm, Tropical Waters
30.03.2015 | Nova Southeastern University

nachricht Misuse of Sustainability Concept May Lead to Even More Toxic Chemical Materials
30.03.2015 | Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Experiment Provides the Best Look Yet at 'Warm Dense Matter' at Cores of Giant Planets

In an experiment at the Department of Energy's SLAC National Accelerator Laboratory, scientists precisely measured the temperature and structure of aluminum as...

Im Focus: Energy-autonomous and wireless monitoring protects marine gearboxes

The IPH presents a solution at HANNOVER MESSE 2015 to make ship traffic more reliable while decreasing the maintenance costs at the same time. In cooperation with project partners, the research institute from Hannover, Germany, has developed a sensor system which continuously monitors the condition of the marine gearbox, thus preventing breakdowns. Special feature: the monitoring system works wirelessly and energy-autonomously. The required electrical power is generated where it is needed – directly at the sensor.

As well as cars need to be certified regularly (in Germany by the TÜV – Technical Inspection Association), ships need to be inspected – if the powertrain stops...

Im Focus: 3-D satellite, GPS earthquake maps isolate impacts in real time

Method produced by UI researcher could improve reaction time to deadly, expensive quakes

When an earthquake hits, the faster first responders can get to an impacted area, the more likely infrastructure--and lives--can be saved.

Im Focus: Atlantic Ocean overturning found to slow down already today

The Atlantic overturning is one of Earth’s most important heat transport systems, pumping warm water northwards and cold water southwards. Also known as the Gulf Stream system, it is responsible for the mild climate in northwestern Europe. 

Scientists now found evidence for a slowdown of the overturning – multiple lines of observation suggest that in recent decades, the current system has been...

Im Focus: Robot inspects concrete garage floors and bridge roadways for damage

Because they are regularly subjected to heavy vehicle traffic, emissions, moisture and salt, above- and underground parking garages, as well as bridges, frequently experience large areas of corrosion. Most inspection systems to date have only been capable of inspecting smaller surface areas.

From April 13 to April 17 at the Hannover Messe (hall 2, exhibit booth C16), engineers from the Fraunhofer Institute for Nondestructive Testing IZFP will be...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

World Conference On Regenerative Medicine 2015: Registration And Abstract Submission Now Open

25.03.2015 | Event News

University presidents from all over the world meet in Hamburg

19.03.2015 | Event News

10. CeBiTec Symposium zum Big Data-Problem

17.03.2015 | Event News

 
Latest News

BLS Cargo orders 15 multisystem locomotives

30.03.2015 | Press release

Shark Tagged by NSU’s Guy Harvey Research Institute Is Apparently Enjoying Time in Warm, Tropical Waters

30.03.2015 | Life Sciences

Antarctic Ice Shelves Rapidly Thinning

30.03.2015 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>