Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Nanoparticle gives antimicrobial ability to fight Listeria longer

08.12.2010
A Purdue University research team developed a nanoparticle that can hold and release an antimicrobial agent as needed for extending the shelf life of foods susceptible to Listeria monocytogenes.

Yuan Yao, an assistant professor of food science, altered the surface of a carbohydrate found in sweet corn called phytoglycogen, which led to the creation of several forms of a nanoparticle that could attract and stabilize nisin, a food-based antimicrobial peptide.

The nanoparticle can then preserve nisin for up to three weeks, combating Listeria, a potentially lethal foodborne pathogen found in meats, dairy and vegetables that is especially troublesome for pregnant women, infants, older people and others with weakened immune systems.

Controlling Listeria at deli counters, for example, is especially problematic because meat is continually being opened, cut and stored, giving Listeria many chances to contaminate the food. Nisin alone is only effective at inhibiting Listeria for a short period - possibly only a few days - in many foods.

"People have been using nisin for a number of years, but the problem has been that it is depleted quickly in a food system," said Arun Bhunia, a Purdue professor of food science who co-authored a paper with Yao on the findings in the early online version of the Journal of Controlled Release. "This nanoparticle is an improved way to deliver the antimicrobial properties of nisin for extended use."

Yao used two strategies to attract nisin to the phytoglycogen nanopoarticles. First, he was able to negatively charge the surface of the nanoparticle and use electrostatic activity to attract the positively charged nisin molecules. Second, he created a partially hydrophobic condition on the surface of the nanoparticle, causing it to interact with partially hydrophobic nisin molecules. When the particles are hydrophobic, or repel water, they become attracted to each other.

"Both strategies may work together to allow nanoparticles to attract and stabilize nisin," Yao said, "This could substantially reduce the depletion of nisin in various systems."

For practical use, Yao said a solution containing the nanoparticles and free nisin could be sprayed onto foods or included in packaging. The solution requires a balance of free nisin and nisin on the nanoparticles.

"When you reduce the amount of free nisin, it will trigger a release of more nisin from the nanoparticles to re-establish the equilibrium," Yao said. "There will be a substantial amount of nisin preserved to counteract the Listeria."

Using a model, Yao said a sufficient amount of nisin to combat Listeria could be preserved for up to 21 days.

Yao and his colleagues are working on using other food-based antimicrobial peptides and nano-constructs to combat Listeria other foodborne pathogens such as E. coli O157:H7 and salmonella. The U.S. Department of Agriculture and the National Science Foundation funded their research.

Writer: Brian Wallheimer, 765-496-2050, bwallhei@purdue.edu

Sources: Yuan Yao, 765-494-6317, yao1@purdue.edu

Arun Bhunia, 765-494-5443, bhunia@purdue.edu

Brian Wallheimer | Purdue University
Further information:
http://www.purdue.edu

More articles from Life Sciences:

nachricht Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery
20.01.2017 | GSI Helmholtzzentrum für Schwerionenforschung GmbH

nachricht Seeking structure with metagenome sequences
20.01.2017 | DOE/Joint Genome Institute

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>