Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Milk and risk of renal cell cancer: Genetic research sheds new light

06.05.2010
While previous research had suggested that drinking milk was related to factors that may increase the risk of renal cell cancer, results of a recent study exploiting the genetic contribution to variation in milk consumption suggest that this may not be the case.

"The data in this study provide no concrete evidence of a need to alter milk drinking in any way," said lead researcher Nicholas Timpson, Ph.D., lecturer in genetic epidemiology at the MRC CAiTE Center in the department of social medicine at the University of Bristol, United Kingdom.

"If anything, the failure of genetic findings to replicate the association between milk and renal cell cancer suggests that fears that milk consumption might elevate cancer risk are likely to be unfounded."

These study results are published in the May issue of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

Previously reported studies suggested a connection between milk intake and renal cell carcinoma risk, and whether this represents a causal association or is the result of bias is currently unclear. Timpson and colleagues used a genetic marker to try to help untangle this observation.

From 1999 through 2003 the researchers conducted a large, hospital-based, case-control study from four central and eastern European countries.

Using observational, genetic and phenotypic data, they determined whether the genetic variant at the gene MCM6 — known to be associated with lactose tolerance — may be used as a non-confounded and unbiased marker for milk consumption's link to cancer risk.

For adult milk drinkers vs. non-milk drinkers in this study, the difference in the odds of renal cell carcinoma was approximately 35 percent. However, when assessing the relationship in a more direct way by using genetic data there was no association between the two.

"We found evidence for the often-questioned relationship between milk consumption and cancer, yet when we used genotypes to verify this relationship, there was no corroboratory evidence," Timpson said. "This does suggest that the basic findings may be subject to the kinds of biases and inaccuracies that often upset epidemiological research, but that this study would need to be undertaken on a much larger scale in order to verify these initial findings."

Johanna Lampe, Ph.D., an editorial board member of Cancer Epidemiology, Biomarkers & Prevention who is not associated with this study, said this study demonstrates the complexities of evaluating dietary exposures and cancer risk.

"These results are a reminder to proceed with caution when interpreting data that suggest an association between intake of specific foods and risk of a particular cancer. Human diet is complex and typically involves adherence to certain dietary patterns that are also tied to other lifestyle behaviors," said Lampe, full member and nutrition scientist in the division of public health sciences at Fred Hutchinson Cancer Research Center, Seattle, Wash.

Subscribe to the AACR RSS News Feed: http://feeds.feedburner.com/aacr

The mission of the American Association for Cancer Research is to prevent and cure cancer. Founded in 1907, the AACR is the world's oldest and largest professional organization dedicated to advancing cancer research. The membership includes 31,000 basic, translational and clinical researchers; health care professionals; and cancer survivors and advocates in the United States and more than 90 other countries. The AACR marshals the full spectrum of expertise from the cancer community to accelerate progress in the prevention, diagnosis and treatment of cancer through high-quality scientific and educational programs. It funds innovative, meritorious research grants, research fellowship and career development awards. The AACR Annual Meeting attracts more than 17,000 participants who share the latest discoveries and developments in the field. Special conferences throughout the year present novel data across a wide variety of topics in cancer research, treatment and patient care. The AACR publishes six major peer-reviewed journals: Cancer Research; Clinical Cancer Research; Molecular Cancer Therapeutics; Molecular Cancer Research; Cancer Epidemiology, Biomarkers & Prevention; and Cancer Prevention Research. The AACR also publishes CR, a magazine for cancer survivors and their families, patient advocates, physicians and scientists. CR provides a forum for sharing essential, evidence-based information and perspectives on progress in cancer research, survivorship and advocacy.

Tara Yates | EurekAlert!
Further information:
http://www.aacr.org

More articles from Life Sciences:

nachricht Symbiotic bacteria: from hitchhiker to beetle bodyguard
28.04.2017 | Johannes Gutenberg-Universität Mainz

nachricht Nose2Brain – Better Therapy for Multiple Sclerosis
28.04.2017 | Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik IGB

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Fighting drug resistant tuberculosis – InfectoGnostics meets MYCO-NET² partners in Peru

28.04.2017 | Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

 
Latest News

Wireless power can drive tiny electronic devices in the GI tract

28.04.2017 | Medical Engineering

Ice cave in Transylvania yields window into region's past

28.04.2017 | Earth Sciences

Nose2Brain – Better Therapy for Multiple Sclerosis

28.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>