The technique, developed by Hsien-Chang Chang, a professor at the Institute of Biomedical Engineering and the Institute of Nanotechnology and Microsystems Engineering, along with former graduate student I-Fang Cheng and their colleagues, is described in the AIP journal Biomicrofluidics.
Using roughened glass slides patterned with gold electrodes, the researchers created microchannels to sort, trap, and identify bacteria. The technique uses surface enhanced Raman spectroscopy. This type of spectroscopy, says Chang, "is based on the measurement of scattered light from the vibration energy levels of chemical bonds following excitation in a craggy metal surface, which enhances the vibration energy." Different components like proteins or other chemical components on the surface of bacteria become attached to the craggy gold zone; when excited, these components cause representative peaks at different wavelengths, creating spectral "fingerprints."
Although some species of bacteria could show very similar signatures because the components on their surfaces are almost the same, says Chang, bacteria from different genera are distinguishable using the technique.
"In the future, different species of fungi could also be sorted based on their different electrical or physical properties by optimizing conditions such as the flow rate, applied voltage, and frequency," he says. "This portable device could be used for preliminary screening for the pathogenic targets in bacteria-infected blood, urethral irritation, and of raw milk and for food monitoring."
The article, " A dielectrophoretic chip with a roughened metal surface for on-chip SERS analysis of bacteria" by I-Fang Cheng (National Cheng Kung University), Chi-Chang Lin (Tunghai University), Dong-Yi Lin and Hsien-Chang Chang (National Cheng Kung University) appears in the journal Biomicrofluidics. http://link.aip.org/link/biomgb/v4/i3/p034104/s1
Journalists may request a free PDF of this article by contacting firstname.lastname@example.org
Jason Socrates Bardi | Newswise Science News
More genes are active in high-performance maize
19.01.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn
How plants see light
19.01.2018 | Albert-Ludwigs-Universität Freiburg im Breisgau
On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.
We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
19.01.2018 | Materials Sciences
19.01.2018 | Health and Medicine
19.01.2018 | Physics and Astronomy