Since cosmetics and hygiene products generally are exposed to air when used, it is important to use air-exposed fragrance compounds when testing a patient for allergic reactions, and not only the pure fragrance compounds.
‘I have developed methods for chemical analysis that for the first time make it possible to identify fragrance compounds that have been exposed to air and thus become potent allergens in small amounts and that people may come in contact with in consumer products,’ says Johanna Rudbäck at the Department of Chemistry and Molecular Biology, University of Gothenburg.
Fragrance compounds are among the most allergenic substances in our environment and are almost always used in cosmetics and hygiene products.
Rudbäck studied two essential oils containing some of the most common fragrance compounds, sweet orange oil and petitgrain oil. The researchers have previously shown that exposing some common fragrance compounds to air leads to the formation of potent allergens, hydroperoxides in particular.
‘My analyses show that hydroperoxides from the fragrance compounds were present already before the bottles were opened, and the levels increased when the oils were exposed to air. The study shows that the oils didn’t have any natural protection against the formation of allergenic compounds,’ says Rudbäck.
To learn more about what happens when exposing fragrance compounds to air, Rudbäck studied two additional commonly used fragrance compounds, alpha-terpinene and citronellol. Alpha-Terpinene is found in for example tea tree oil and citronellol, from geranium, is one of the six most common fragrance compounds in cosmetics and hygiene products.
The hydroperoxides from the fragrance compounds are generally difficult to identify and quantify. They are unstable and lack UV absorbance, and are very similar and come in several different forms. In addition, they are found in low concentrations in complex mixtures. The new methods involve separation of the hydroperoxides using either liquid or gas chromatography and detection using mass spectrometry.
‘According to EU regulations, cosmetics must be specially labelled when containing fragrance allergens in concentrations exceeding 0.001% in stay-on products such as lotions and 0.01% in rinse-off products such as shampoos,’ says Rudbäck.
Title of the doctoral thesis: Allergenic Oxidation Products from Fragrance Terpenes – Chemical Analysis and Determination of Sensitizing PotencyContact: Johanna Rudbäck, Department of Chemistry and Molecular Biology
Torsten Arpi | idw
Toward a 'smart' patch that automatically delivers insulin when needed
18.01.2017 | American Chemical Society
127 at one blow...
18.01.2017 | Stiftung Zoologisches Forschungsmuseum Alexander Koenig, Leibniz-Institut für Biodiversität der Tiere
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...
10.01.2017 | Event News
09.01.2017 | Event News
05.01.2017 | Event News
18.01.2017 | Power and Electrical Engineering
18.01.2017 | Materials Sciences
18.01.2017 | Life Sciences