Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Malaria protection in chimpanzees

29.05.2013
Researchers found that adult wild chimpanzees have developed a certain immunity against malaria parasites

Wild great apes are widely infected with malaria parasites. Yet, nothing is known about the biology of these infections in the wild. Using faecal samples collected from wild chimpanzees, an international team of researchers from the Max Planck Institute for Evolutionary Anthropology in Leipzig and the Robert Koch Institute in Berlin has now investigated the effect of the animals’ age on malaria parasite detection rates.


Group of chimpanzees, Taï National Park, Cote d’Ivoire. © Sonja Metzger

The data show a strong association between age and malaria parasite positivity, with significantly lower detection rates in adult chimpanzees. This suggests that, as in humans, individuals reaching adulthood have mounted an effective protective immunity against malaria parasites.

In malaria regions the parasite prevalence in the human body as well as malaria-related morbidity and mortality decrease with age. This reflects the progressive mounting of a protective immunity. Researchers of the Max Planck Institute for Evolutionary Anthropology and the Robert Koch-Institute now present a study which addresses the age distribution of malaria parasite infection in a group of wild chimpanzees.

To this end the researchers collected 141 faecal samples from seven female and 12 male wild chimpanzees from Taï National Park, Cote d’Ivoire. At time of sampling the animals’ ages ranged between 3 and 47 years. The researchers extracted DNA from the faecal samples, analysed it and so identified the malaria parasite-positive samples. “In the course of this 2-month study almost every individual chimpanzee of the group was found positive at least once”, says Hélène De Nys of the Max Planck Institute for Evolutionary Anthropology and the Robert Koch-Institute. “Our data further suggest that at every point in time at least one individual of this chimpanzee group is infected”.

Further analyses showed that malaria parasites were detected more often in younger than in older animals. Whether these were female or male, however, did not make a difference. “This is the first indication that epidemiological characteristics of malaria parasite infection in wild chimpanzee populations might be comparable to those in human populations”, says Roman Wittig of the Max Planck Institute for Evolutionary Anthropology. “As in humans, the development of acquired immunity likely plays an important role in wild chimpanzees as well”.

Throughout this process, malaria parasites might also contribute directly to decimating young chimpanzees. During analyses performed on more than 30 dead adult chimpanzees from the same community malaria could be excluded as the cause of death. For young chimpanzees, however, the question remains open. While it is known that mortality in young chimpanzees is high, their bodies are rarely accessible. This is because they are less likely to be found and because their carcasses are carried for several days by their mothers.

“Even though at this stage, we cannot pinpoint pathogenicity of malaria parasites found in wild chimpanzees, our results suggest a continuous exposure of this population, leading to the development of a certain resistance to infection”, says Fabian Leendertz of the Robert Koch-Institute.

Contact

Dr. Roman Wittig
Max Planck Institute for Evolutionary Anthropology, Leipzig
Phone: +49 341 3550-204
Email: wittig@­eva.mpg.de
Dr. Fabian Leendertz
Robert Koch Institute
Phone: +49 30 18754-2592
Email: LeendertzF@­rki.de
Sandra Jacob
Press and Public Relations
Max Planck Institute for Evolutionary Anthropology, Leipzig
Phone: +49 341 3550-122
Fax: +49 341 3550-119
Email: jacob@­eva.mpg.de

Original publication
Hélène M. De Nys, Sébastien Calvignac-Spencer, Ursula Thiesen, Christophe Boesch, Roman M. Wittig, Roger Mundry & Fabian H. Leendertz
Age-related effects on malaria parasite infection in wild chimpanzees
Biology Letters, 29 May 2013, DOI: http://dx.doi.org/10.1098/rsbl.2012.1160

Dr. Roman Wittig | Max-Planck-Institute
Further information:
http://www.mpg.de/7270582/chimpanzees-protection_malaria

More articles from Life Sciences:

nachricht Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery
20.01.2017 | GSI Helmholtzzentrum für Schwerionenforschung GmbH

nachricht Seeking structure with metagenome sequences
20.01.2017 | DOE/Joint Genome Institute

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>