Valio's Lactobacillus rhamnosus GG (LGG®) is the most frequently studied and used probiotic. Under the supervision of researchers at the Institute of Biotechnology, and the Department of Basic Veterinary Sciences at the University of Helsinki, an international research team determined the genome sequences of LGG and a bacterium closely related to it.
The results, published in the renowned PNAS journal, shed light on the origin of probiotic mechanisms and promote product development in the food industry.
Functional food includes products designed for daily use, which have been shown by clinical studies to have positive health effects. Scientific study results have particularly contributed to the success of dairy products containing probiotic bacteria. Many research publications have confirmed that these bacteria promote health and boosts immune system and improve digestion. Some probiotics can also alleviate the symptoms suffered by those with irritable bowel syndrome. As many as every fifth westerner suffers from this pain, also called spastic colon. Studies say that LGG probiotics are also an effective treatment method for reducing children's atopic symptoms, and the risk of respiratory infections.
In its recent publication, the research team showed that the protein component found by the team has a fundamental role in LGG binding with the human intestinal mucus. The team found out that the surface structures of LGG has a specific adhesion component. Remarkably, the binding feature has been assumed to be one of the most important characteristics of bacteria with health-benefiting effects. Moreover, the researchers assume that the protein structure in question enables the health-promoting effects of LGG and other probiotic bacteria, and the positive immune modulation produced by them.
The research is a prime example of productive co-operation between researchers and the food industry. According to Tuomas Salusjärvi, research manager for Valio, the successful sequencing provides valuable additional information to support the already existing research information. The safety of the LGG probiotic and its advantages to consumers can now be shown in an even better way than before. A significant research field has been established around probiotic bacteria. So far, thousands of scientific articles have been published on the subject. For this line of research, the findings of the genome, and the molecular mechanism possibly behind probiotics, is a downright breakthrough.
The original publication is available online at: http://www.pnas.org/content/early/2009/09/16/0908876106.abstract
The research has been funded by the Academy of Finland, and the Finnish Funding Agency for Technology and Innovation (TEKES).Additional information:
Matti Kankainen | EurekAlert!
Designer cells: artificial enzyme can activate a gene switch
22.05.2018 | Universität Basel
Flow of cerebrospinal fluid regulates neural stem cell division
22.05.2018 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt
At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.
At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...
There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.
The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...
02.05.2018 | Event News
13.04.2018 | Event News
12.04.2018 | Event News
22.05.2018 | Life Sciences
22.05.2018 | Earth Sciences
22.05.2018 | Trade Fair News