Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Lice can be nice to us

28.04.2009
Parasite infestations might have a good side. Wild mice from a Nottinghamshire forest have given experts at The University of Nottingham clues as to the importance of some parasites, such as lice, for the conditioning of a “natural” immune system.

Jan Bradley, Professor of Parasitology, said: “Our understanding of mammalian immunology is largely based on rodents reared under highly unnatural pathogen and stress-free conditions. Analysing the immune response in wild populations can give crucial insights into how the immune system functions in its natural context.”

Many health problems in modern humans are caused by over-active immune responses. The immune system should be able to tell the difference between foreign invaders and its own body cells. But sometimes it can mistake self proteins for non self proteins triggering an attack on its own body and causing an autoimmune disease such as arthritis, asthma, diabetes or multiple sclerosis. Or the body can mistake a harmless substance as a threat causing an allergic response.

The authors say some parasites may exert a moderating effect on the function of a key component of the immune system, which could help reduce overall immune reactivity and the risk of developing immune dysfunctions.

Their research, published in the open access journal BMC Biology, links the louse Polyplax serrata to a strong dampening of certain immune responses in wild wood mice. This implies that other mammals, such as modern humans, that develop in artificial environments may have less regulated, overactive immune systems precisely because they are not exposed to parasites throughout their lives.

The researchers speculate that the louse is able to exert some kind of immuno-suppressive effect, possibly directly by secreting some substance into the mice from its saliva, or indirectly by transmitting bacteria or other pathogens.

Professor Bradley said: “Much like laboratory mice, people in developed countries are currently exposed to a very different profile of infections to that encountered by their ancestors. It is possible that the immune dysfunctions we see today are the result of immune systems moulded by evolution for a set of challenges completely different to those encountered in modern times.”

Lindsay Brooke | EurekAlert!
Further information:
http://www.nottingham.ac.uk
http://communications.nottingham.ac.uk/News/Article/Lice-can-be-nice-to-us.html

More articles from Life Sciences:

nachricht Modern genetic sequencing tools give clearer picture of how corals are related
17.08.2017 | University of Washington

nachricht The irresistible fragrance of dying vinegar flies
16.08.2017 | Max-Planck-Institut für chemische Ökologie

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

Climate change: In their old age, trees still accumulate large quantities of carbon

17.08.2017 | Earth Sciences

Modern genetic sequencing tools give clearer picture of how corals are related

17.08.2017 | Life Sciences

Superconductivity research reveals potential new state of matter

17.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>