Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Iron-based process promises greener, cheaper and safer drug and perfume production

02.12.2013
University of Toronto researchers have developed a series of techniques to create a variety of very active iron-based catalysts necessary to produce the alcohols and amines used in the drug and perfume industry. The new synthetic methods promise to be safer and more economical and environmentally friendly than traditional industrial processes.

The research takes advantage of Earth's extensive supply of iron – the fifth most abundant naturally occurring metal – substituting it in place of the rare elements of ruthenium, rhodium, palladium and platinum traditionally used in the design of hydrogenation catalysts. The result is an exceptionally efficient class of iron complexes whose abilities rival and even surpass those of conventional industrial catalysts.

"There is a research effort world-wide to make chemical processes more sustainable and green by replacing the rare, expensive and potentially toxic elements used in hydrogenation, catalytic converters in cars, fuel cells for the efficient conversion of chemical energy into electricity, and silicone coatings, with abundant ions such as iron," says U of T chemistry professor Robert Morris, principal investigator of a study reported in the November 29 issue of Science. "Iron is about 10,000 times cheaper to obtain than ruthenium. And less than 200 metric tons of platinum-type metals are mined in the world every year, not all of it can be recycled after use, it is not essential to life, and it can be toxic."

"We found a way to make the ferrous form of iron behave in a catalytic process much more efficiently than a precious metal. We did this by finding molecules containing nitrogen, phosphorus, carbon and hydrogen, that bond to, and enhance, the reactivity of iron," says Morris.

The scientists inexpensively produced varieties of alcohol with different biological properties – which can be used in flavour and drug synthesis – and different smells, a property important to the perfume industry. In one example from the study, the precursor alcohol to a cancer treatment can be made using the hydrogenation process catalyzed by iron. Using iron, the resulting complex is often a better catalyst than the industrial one based on ruthenium.

The sustainable technology incubator GreenCentre Canada is already pursuing the commercialization of the new iron catalysts.

Funding for this research was provided by the Natural Sciences and Engineering Research Council of Canada and GreenCentre Canada.

MEDIA CONTACTS:

Robert Morris
Department of Chemistry
University of Toronto
416-978-6962
robert.morris@utoronto.ca
Sean Bettam
Communications
Faculty of Arts & Science
University of Toronto
416-946-7950
s.bettam@utoronto.ca

Sean Bettam | EurekAlert!
Further information:
http://www.utoronto.ca

More articles from Life Sciences:

nachricht At last, butterflies get a bigger, better evolutionary tree
16.02.2018 | Florida Museum of Natural History

nachricht New treatment strategies for chronic kidney disease from the animal kingdom
16.02.2018 | Veterinärmedizinische Universität Wien

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

Im Focus: Interference as a new method for cooling quantum devices

Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters

Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...

Im Focus: Autonomous 3D scanner supports individual manufacturing processes

Let’s say the armrest is broken in your vintage car. As things stand, you would need a lot of luck and persistence to find the right spare part. But in the world of Industrie 4.0 and production with batch sizes of one, you can simply scan the armrest and print it out. This is made possible by the first ever 3D scanner capable of working autonomously and in real time. The autonomous scanning system will be on display at the Hannover Messe Preview on February 6 and at the Hannover Messe proper from April 23 to 27, 2018 (Hall 6, Booth A30).

Part of the charm of vintage cars is that they stopped making them long ago, so it is special when you do see one out on the roads. If something breaks or...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

Fingerprints of quantum entanglement

16.02.2018 | Information Technology

'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers

16.02.2018 | Health and Medicine

Hubble sees Neptune's mysterious shrinking storm

16.02.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>