Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


New hope for patients - Researchers at Hohenstein successfully colonise a textile implant with human stem cells

Stem cells are widely considered a major new hope in medicine because they are capable of differentiating into a broad variety of human cell types.

This characteristic makes them particularly interesting for recreating irreversibly damaged tissues, following a heart attack for example, or in cases of injury to the spinal cord.

Researchers at the Institute for Hygiene and Biotechnology (IHB) at the Hohenstein Institute have successfully devised a special, optimised textile coating that allows adult human stem cells to colonise the surface fibres of textile implants. A molecular layer of natural biomaterials from the human extra-cellular matrix has been developed for this purpose.

Cell colonies derived from the body cells of the patient allow the tiny "all-rounders" to be placed directly at the site of damaged tissue. New cardiac muscle cells, for example, can be generated by introducing certain factors. These can then be used to replace parts of the heart that have been destroyed during a heart attack.

The head of the IHB, Dr. Dirk Hoefer says, "This is an initial success in the direction of textile stem cell therapy. But we still need to develop better understanding of how stem cells colonise - meaning interact with - fibres. Therefore, we will continue working on optimising colonisation of textile implants in order to provide as many cells as possible per unit of fibre surface and with the required factors in a targeted way. "

Adult stem cells are found in many types of human tissues and, unlike embryonic stem cells, do not have to be harvested from human embryos, a controversial approach that is frequently rejected on ethical grounds. The mesenchymal stem cells used by the scientists are multipotent, meaning that they can, for example, develop into heart muscle, bone or cartilaginous tissue. Colonising stem cells on textiles opens up far-reaching therapeutic possibilities for regenerative medicine. Textile implants are frequently used during surgery requiring the stabilisation of injured tissue. There are, for example, heart patches made of biomaterial that can be applied to damaged cardiac tissues. After a certain time, the implanted biodegradable foreign objects are dissolved by the patient's body.

The aim of the researchers at Hohenstein is to colonise diverse textiles with human stem cells in the laboratory and then to convert them directly into the cell type of the target tissue. The scientists are also currently working on a technique for colour-marking the stem cells in order to make it possible to identify them even after differentiation into heart, cartilage or bone tissue, as well as ease following the post-implantation progress of colonised textiles.

Rose-Marie Riedl | idw
Further information:

More articles from Life Sciences:

nachricht International team discovers novel Alzheimer's disease risk gene among Icelanders
24.10.2016 | Baylor College of Medicine

nachricht New bacteria groups, and stunning diversity, discovered underground
24.10.2016 | DOE/Lawrence Berkeley National Laboratory

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

New method increases energy density in lithium batteries

24.10.2016 | Power and Electrical Engineering

International team discovers novel Alzheimer's disease risk gene among Icelanders

24.10.2016 | Life Sciences

New bacteria groups, and stunning diversity, discovered underground

24.10.2016 | Life Sciences

More VideoLinks >>>