Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Hope for a rabies eradication strategy in Africa

21.01.2009
Most of the rabies virus circulating in dogs in western and central Africa comes from a common ancestor introduced to the continent around 200 years ago, probably by European colonialists.

In the current issue of Journal of General Virology a team of scientists from Africa, USA and France report that within this common ancestry there are distinct subspecies at country level and that there is only limited movement of virus between localities.

These factors mean that, if neighbouring countries collaborate, a progressive strategy to eliminate rabies from this area of sub-Saharan Africa is possible.

Rabies causes over 24,000 deaths a year in Africa, mostly in poor rural communities and of children. Rabies prevention and treatment are costly and the necessary resources often scarce or inadequate. Controlling rabies in dogs, the main agents of rabies spread, is therefore an important part of any rabies eradication programme.

The team analysed 182 samples of dog rabies virus from 27 African countries taken over a time period of 29 years. Their analyses showed that the samples were of two types, which they call "Africa 1" and “Africa 2” with different geographical distribution and history, indicating a clear distinction between rabies viruses circulating in North Africa and those circulating in West/Central Africa. It appeared that “Africa 2” was introduced into the eastern part of West/Central Africa – probably in Chad – around 200 years ago and from there spread over the whole region, moving westwards and southwards, over a 100-year period. This spread follows the pattern of French colonial expansion in Africa. Distinct subpopulations of the virus exist in the different African countries and there is very little evidence that there is much movement of the virus among localities.

Dr Hervé Bourhy, from the Institut Pasteur in Paris who led the research said:

“Some scientists have suggested that rabies outbreaks in Africa might be caused by “superspreader” dogs, transmitting the disease over large distances. Our findings show that this is extremely unlikely as there is strong geographical clustering of the dog rabies subspecies and the time-scale for diffusion of the virus is measured in decades. Similarly, people transporting dogs, some of them eventually becoming infectious or in incubation, over this vast region does not seem to have had much, if any, impact on the spread of disease”.

Chiraz Talbi, the researcher who carried out the analysis, added: “Rabies kills a patient, most often a child, every 20 minutes in Africa. By identifying the species of the virus that is the most prevalent and demonstrating how it spreads through the region, we have shown that, with collaboration, it should be possible for African countries to eliminate rabies by controlling dog rabies”.

Dianne Stilwell | alfa
Further information:
http://jgv.sgmjournals.org/misc/direct.shtml
http://www.sgm.ac.uk

More articles from Life Sciences:

nachricht Single-stranded DNA and RNA origami go live
15.12.2017 | Wyss Institute for Biologically Inspired Engineering at Harvard

nachricht New antbird species discovered in Peru by LSU ornithologists
15.12.2017 | Louisiana State University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>