In the current issue of Journal of General Virology a team of scientists from Africa, USA and France report that within this common ancestry there are distinct subspecies at country level and that there is only limited movement of virus between localities.
These factors mean that, if neighbouring countries collaborate, a progressive strategy to eliminate rabies from this area of sub-Saharan Africa is possible.
Rabies causes over 24,000 deaths a year in Africa, mostly in poor rural communities and of children. Rabies prevention and treatment are costly and the necessary resources often scarce or inadequate. Controlling rabies in dogs, the main agents of rabies spread, is therefore an important part of any rabies eradication programme.
The team analysed 182 samples of dog rabies virus from 27 African countries taken over a time period of 29 years. Their analyses showed that the samples were of two types, which they call "Africa 1" and “Africa 2” with different geographical distribution and history, indicating a clear distinction between rabies viruses circulating in North Africa and those circulating in West/Central Africa. It appeared that “Africa 2” was introduced into the eastern part of West/Central Africa – probably in Chad – around 200 years ago and from there spread over the whole region, moving westwards and southwards, over a 100-year period. This spread follows the pattern of French colonial expansion in Africa. Distinct subpopulations of the virus exist in the different African countries and there is very little evidence that there is much movement of the virus among localities.
Dr Hervé Bourhy, from the Institut Pasteur in Paris who led the research said:
“Some scientists have suggested that rabies outbreaks in Africa might be caused by “superspreader” dogs, transmitting the disease over large distances. Our findings show that this is extremely unlikely as there is strong geographical clustering of the dog rabies subspecies and the time-scale for diffusion of the virus is measured in decades. Similarly, people transporting dogs, some of them eventually becoming infectious or in incubation, over this vast region does not seem to have had much, if any, impact on the spread of disease”.
Chiraz Talbi, the researcher who carried out the analysis, added: “Rabies kills a patient, most often a child, every 20 minutes in Africa. By identifying the species of the virus that is the most prevalent and demonstrating how it spreads through the region, we have shown that, with collaboration, it should be possible for African countries to eliminate rabies by controlling dog rabies”.
Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery
20.01.2017 | GSI Helmholtzzentrum für Schwerionenforschung GmbH
Seeking structure with metagenome sequences
20.01.2017 | DOE/Joint Genome Institute
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
20.01.2017 | Awards Funding
20.01.2017 | Materials Sciences
20.01.2017 | Life Sciences