Published 2011 June 4;12(1):291[Epub ahead of print], in BMC Genomics, the results of comparison using a whole genome approach with three isolates and focused PCR assay on over 70 isolates demonstrated that A. baumannii is a diverse and genomically variable pathogen that appears to have the potential to cause a range of human disease, regardless of the isolation source.
Acinetobacter baumannii has emerged as a significant global pathogen, due to its persistence in the hospital environment, rapid acquisition of antibiotic resistance and the broad spectra of its antimicrobial resistance patterns. It has spread rapidly within hospitals and health care institutions. These features have made A. baumannii a highly studied emerging pathogen in the heath care setting.
This study could have only been completed with the assembled interdisciplinary team of epidemiologists, clinical laboratory personnel, bioinformaticians and microbial genomics researchers from the Institute for Genome Sciences (IGS) and Epidemiology & Public Health at the University of Maryland School of Medicine.
Dr. Anthony Harris, Director of the Division of Genomic Epidemiology and Clinical Outcomes and co-author on the paper highlights that "additional genomic research needs to be done to elucidate why Acinetobacter baumanii has emerged as a hospital pathogen and what is contributing to its patient-to-patient spread. This study gets us closer to that goal".
“This study provides insight into the genomic variability of A. baumannii within a hospital setting and body sites, which will allow us a better understanding of the basic processes of this emerging pathogen.” commented Dr. Rasko, the corresponding author on the study.
Sarah Pick | Newswise Science News
Discovery of a Key Regulatory Gene in Cardiac Valve Formation
24.05.2017 | Universität Basel
Carcinogenic soot particles from GDI engines
24.05.2017 | Empa - Eidgenössische Materialprüfungs- und Forschungsanstalt
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.
In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...
23.05.2017 | Event News
22.05.2017 | Event News
17.05.2017 | Event News
24.05.2017 | Earth Sciences
24.05.2017 | Life Sciences
24.05.2017 | Life Sciences