The study is set for publication the week of Feb. 20 in the early edition of the Proceedings of the National Academy of Sciences.
"Many disease-causing microbes can evade one defensive action by a host plant, but we believe that most microbes would have difficulty overcoming a combination of two immune-system defenses," said UC Davis plant sciences professor Abhaya Dandekar, the lead researcher.
He and his colleagues tested this hypothesis on Xylella fastidiosa, the bacteria responsible for Pierce's disease in grapevines. Strains of the bacteria also attack and damage other host plants, including citrus, stone fruits, almonds, oleander, and certain shade trees, such as oaks, elms, maples and sycamores.
The findings further strengthen UC Davis' standing as a world leader in the science of plant improvement through advances in genetics, genomics, plant breeding and biodiversity.
First noted in California near Anaheim around 1884, Pierce's disease in grapevines is now known to exist in 28 California counties. From 1994 to 2000, the disease destroyed more than 1,000 acres of northern California grapevines, causing $30 million in damages. There is currently no known cure for Pierce's disease.
In grapevines, Xylella fastidiosa is carried from plant to plant by half-inch-long insects known as sharpshooters. The bacteria infect and clog the plant's water-transporting tissue, or xylem. Grapevines with Pierce's disease develop yellow and brown leaves and die within a few years.
To block such infections, the researchers engineered a hybrid gene by fusing together two genes that are responsible for two key functions of the plant's innate immune response: recognizing Xylella fastidiosa as a bacterial invader and destroying its outer membranes, causing the bacteria to die.
The researchers then inserted this hybrid gene into grapevines.
They found that sap from plants genetically engineered with the hybrid gene effectively killed Xylella fastidiosa in the laboratory. And grapevines engineered to carry the hybrid gene had significantly less leaf scorching and xylem clogging, indicating resistance to Pierce's disease.
The Los Alamos National Laboratory, New Mexico, and the U.S. Department of Agriculture collaborated on the project. Funding came from the state Department of Food and Agriculture's Pierce's Disease Program, the U.S. Department of Energy and the U.S. Department of Agriculture.
About UC Davis:
For more than 100 years, UC Davis has engaged in teaching, research and public service that matter to California and transform the world. Located close to the state capital, UC Davis has more than 32,000 students, more than 2,500 faculty and more than 21,000 staff, an annual research budget that exceeds $684 million, a comprehensive health system and 13 specialized research centers. The university offers interdisciplinary graduate study and more than 100 undergraduate majors in four colleges — Agricultural and Environmental Sciences, Biological Sciences, Engineering, and Letters and Science. It also houses six professional schools — Education, Law, Management, Medicine, Veterinary Medicine and the Betty Irene Moore School of Nursing.
Media contact(s):Abhaya Dandekar, Plant Sciences, (530) 752-7784, email@example.com
Patricia Bailey | EurekAlert!
Atomic-level motion may drive bacteria's ability to evade immune system defenses
24.04.2017 | Indiana University
Two-dimensional melting of hard spheres experimentally unravelled after 60 years
24.04.2017 | University of Oxford
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
20.04.2017 | Event News
18.04.2017 | Event News
03.04.2017 | Event News
24.04.2017 | Physics and Astronomy
24.04.2017 | Materials Sciences
24.04.2017 | Life Sciences