Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Fruit fly's 'sweet tooth' short-lived: U of British Columbia research

17.10.2012
The humble fruit fly may have something to teach us about forgoing empty calories for more nutritional ones – especially when we're hungry.

While the flies initially prefer food with a sweet flavour, they quickly learn to opt for less sweet food sources that offer more calories and nutritional value, according to new research by University of British Columbia zoologists.

The findings, published this week in the Journal of Neuroscience, are the first to measure the shift in food preference over time, and the first to find that flies opt for nutritious food more quickly when they're hungry.

NB: A high resolution, close up photo of a fruit fly feeding on a strawberry is available at: http://science.ubc.ca/fly_strawberry_Mike_Gordon_UBC.jpg.

"The taste system is important for quick – often life and death – decisions about what to eat," says Michael Gordon, a UBC neurobiologist and senior author on the paper. "Typically the initial taste of sugar indicates a good source of carbohydrates, but longer-term feeding preferences integrate past experiences and learning. It appears that nutritional content is an important part of that."

"From a behavioural standpoint, it seems that mammals and flies can show similar responses to calorie sensing," adds Gordon, an assistant professor with the Department of Zoology. "But mechanistically we're still only beginning to understand how either senses the caloric value of food independently of taste after eating it."

The researchers allowed fruit flies (Drosophila melanogaster) to choose between sources of liquid sugar that varied in their ratios of sweetness to caloric value. In some instances it took the populations of flies as little as four hours to shift their preference towards more nutritious food sources – typically based on sugars like sucrose, maltose and D-glucose.

Researchers also isolated several molecular pathways in a strain of flies that appear to affect taste and feeding preference and found that blocking insulin signaling increased preference for nutritious sugars.

BACKGROUND | Fruit flies opt for nutrition

Research Method

In addition to observing food preferences, the UBC research team also used mutant strains of fruit flies to isolate several molecular pathways that appear to affect taste and feeding preference. They found that developing a preference for caloric sugars depends on the cAMP pathway, which plays a wide array of roles in the nervous system but is best known for affecting learning and memory.

The researchers also found that blocking insulin signaling in a strain of flies increased their preference for nutritious sugars. Insulin plays important metabolic roles in both flies and mammals and is known to be regulated by feeding. The regulating of feeding behaviour by insulin signaling has also been demonstrated in mammals.

Funding Partners

The research was supported by the Canadian Institutes of Health Research and the Natural Sciences and Engineering Research Council of Canada.

Photo Caption

Photo: Fruit fly (Drosophila melanogaster) feeding on a strawberry. Credit: Michael Gordon, the University of British Columbia.

Chris Balma | EurekAlert!
Further information:
http://www.ubc.ca

More articles from Life Sciences:

nachricht Nanoparticle Exposure Can Awaken Dormant Viruses in the Lungs
16.01.2017 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

nachricht Cholera bacteria infect more effectively with a simple twist of shape
13.01.2017 | Princeton University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

Im Focus: How to inflate a hardened concrete shell with a weight of 80 t

At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).

Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...

Im Focus: Bacterial Pac Man molecule snaps at sugar

Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.

The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

Nothing will happen without batteries making it happen!

05.01.2017 | Event News

 
Latest News

Water - as the underlying driver of the Earth’s carbon cycle

17.01.2017 | Earth Sciences

Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

17.01.2017 | Materials Sciences

Smart homes will “LISTEN” to your voice

17.01.2017 | Architecture and Construction

VideoLinks
B2B-VideoLinks
More VideoLinks >>>