Fish is healthy: easy to digest and with a high level of precious proteins, fish is considered an important part of a healthy diet. And with the so-called omega-3 fatty acids fish contains real ‘fountains of youth‘.
These fatty acids – like docosahexaeonic acid (DHA) occur mostly in fatty fish like herring, salmon and mackerel. They are thought to lower the blood pressure, to strengthen the immune system and to have positive effects on the development on the nervous system and the cardiovascular system.“Clinical studies about the intake of nutritional supplements containing omega-3 fatty acids haven’t provided complete clarity so far,“ Prof. Dr. Stefan H. Heinemann from Friedrich Schiller University Jena (Germany) says. “The molecular impact of the omega-3 fatty acids isn’t fully understood yet,” the biophysicist continues. But now scientists of the DFG research group FOR 1738 based at Jena University are able to bring new facts to light: in two newly published articles for the well-known science magazine ‘Proceedings of the National Academy of Sciences, USA’ they describe how they analyzed the impact of omega-3 fatty acids on a systemic level and they also described the underlying molecular mechanisms for the first time.
Prof. Bauer and his colleagues examined the effects of omega-3 fatty acids on SLO1 channels of the cardiovascular system by experimenting with mice. “Administration of DHA should result in an expansion of the blood vessels and consequently a drop in blood pressure,” the physician says. The laboratory experiments confirmed exactly that. In genetically modified mice however, which were not able to produce the SLO1 channel, the antihypertensive impact of DHA failed to appear. ”Thus we were able to show for the first time that DHA directly influences the blood pressure, which is being mediated through SLO1 channels,” Bauer summarizes.
Beyond that, the scientists made another surprising discovery: a variant of DHA, which can often be found in nutritional supplements containing omega-3 fatty acids, doesn’t show an antihypertensive effect. Moreover, it suppresses and even diminishes the effect of the natural DHA from fish oil. “The intake of non-natural omega-3 fatty acids can therefore also have counter-productive effects,” Prof. Bauer stresses. This is of particular importance for the nutritional supplements of patients in intensive care who are being drip-fed: their supplements of omega-3 fatty acids should be specifically aimed at and adapted to the patients’ clinical requirements.Original Publications:
Dr. Ute Schönfelder | idw
Not of Divided Mind
19.01.2017 | Hertie-Institut für klinische Hirnforschung (HIH)
CRISPR meets single-cell sequencing in new screening method
19.01.2017 | CeMM Forschungszentrum für Molekulare Medizin der Österreichischen Akademie der Wissenschaften
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
19.01.2017 | Earth Sciences
19.01.2017 | Life Sciences
19.01.2017 | Physics and Astronomy