Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Fish cancer gene linked to pigment pattern that attracts mates

20.08.2008
Swordtails can inherit melanoma that drives sexual selection

Though skin cancer is deadly to male fish, it also has one perk: The black melanoma splotches arise from attractive natural markings that lure female mates.

A new study published in the Proceedings of the National Academy of Sciences this week shows that the melanoma gene can be conserved in swordtail fish because of its beneficial role in sexual selection.

Ohio University scientists André Fernandez and Molly Morris studied three populations of female swordtails, tiny freshwater fish native to North and Central America, and found that two of them preferred males whose tails were painted to resemble the skin cancer spots. The researchers also examined specimens of swordtail fish with real melanomas, which confirmed that the cancer gene is switched on only in the tissue with the dark pigment. The study marks the first time scientists have found a cancer gene linked to a pigment pattern that functions to increase mating success in animals.

In the current study, the researchers placed a female swordtail in the middle of a tank with two partitions. They positioned a male with the faux pattern from which melanomas form on one side, and a male without the pattern on the other. After releasing the female from an opaque tube into the tank's center chamber, the scientists observed how much time she spent looking at each male during an eight-minute period. The project builds on previous studies in the Morris lab, which used the same tests to show that female swordtails are strongly attracted to males with dark vertical bars.

To avoid any bias the female might have for a particular side of the tank, Fernandez then switched the males. Two days later, he conducted the trials again, this time changing which male received the painted skin cancer spot. The female consistently chose the male with the dark pigmented marking in two of the three populations, he said.

But the research suggests that the swordtail fish population also keeps the prevalence of the cancer gene in check. A third population of females in the study rejected the males painted with the pattern that can form melanomas. The scientists suspect that's because the third group had a higher ratio of both males and females with the gene for skin cancer, which increases the likelihood of too many offspring inheriting the gene and dying off.

Swordtail fish usually live for 1.5 to 2 years in the wild and sexually mature at 4.5 months. The ones with the skin cancer gene can develop melanomas at about 7 months and die a few months later.

"Melanoma formation cuts the reproductive life cycle in half," Fernandez said. "It has a huge cost for males."

But during the few months when the male is sexually mature and healthy, he also can produce a lot of offspring, he noted.

The swordtail melanoma has been studied since the 1920s, and scientists previously believed that fish developed the cancer only in captivity. But in the recent study, 10 percent of the swordtails collected from the third population in Mexico also exhibited the disease, said Fernandez, who joins the University of Texas M.D. Anderson Cancer Center this fall as a postdoctoral fellow. He hopes to conduct further studies on the habitat, such as whether stronger exposure to the sun's UV rays might be driving more instances of skin cancer in the wild.

Andrea Gibson | EurekAlert!
Further information:
http://www.ohio.edu

More articles from Life Sciences:

nachricht Modern genetic sequencing tools give clearer picture of how corals are related
17.08.2017 | University of Washington

nachricht The irresistible fragrance of dying vinegar flies
16.08.2017 | Max-Planck-Institut für chemische Ökologie

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

Gold shines through properties of nano biosensors

17.08.2017 | Physics and Astronomy

Greenland ice flow likely to speed up: New data assert glaciers move over sediment, which gets more slippery as it gets wetter

17.08.2017 | Earth Sciences

Mars 2020 mission to use smart methods to seek signs of past life

17.08.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>