Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

European REACH Legislation for Chemicals May Require More Animals and Funds than Estimated

28.08.2009
The European Union’s REACH (Registration, Evaluation, Authorization and Restriction of Chemical) legislation is intended as a comprehensive safety evaluation for commercial chemicals used in consumer products that are traded in Europe at amounts more than one ton per year.

However, implementation of the regulation may require 54 million research animals and €9.5 billion ($13.4 billion) over the next 10 years, which represents 20 times the number of animals and six times the cost anticipated in previous estimates, according to an analysis led by researchers at the Johns Hopkins Bloomberg School of Public Health.

Currently, the EU uses approximately 900,000 animals at a cost of €600 million ($847 million) per year to evaluate new chemicals, drugs, pesticides and food additives. A commentary on the research is published in the August 26 edition of Nature. The full analysis will appear the same day as an electronic prepublication of the September 2009 edition of the journal ALTEX, Alternatives to Animal Experimentation.

“As a toxicologist, I support the aims of REACH—it is the biggest investment into consumer safety ever,” said study author, Thomas Hartung, MD, PhD, Doerenkamp-Zbinden Professor and Chair for Evidence-based Toxicology and director of the Center for Alternatives to Animal Testing (CAAT) at the Bloomberg School of Public Health. “However, I am concerned that we have underestimated the scale of the challenge. Investment into developing alternative research methods to meet REACH goals is urgently needed.”

According to Hartung and co-author Constanza Rovida, estimates for the number of chemicals to be covered by REACH range from 68,000 to 101,000, which is higher than the earlier estimate of 29,000 chemicals. The analysis was based on the conservative estimate of 68,000 registered chemicals. Results showed that 90 percent of the projected animal use and 70 percent of the projected cost would come from research into reproductive toxicity testing. This often requires that data be collected from two species of test animals and their offspring. The U.S. Environmental Protection Agency regulations do not include two-species provisions.

“A revision of test approaches especially for reproductive toxicity is essential. There is no alternative to REACH, but there will be no REACH without alternatives,” said Hartung.

Further discussions of REACH and alternative testing methods will be addressed at the 7th World Congress on Alternatives & Animal Use in the Life Sciences held in Rome, Italy, August 30 to September 3. The meeting is co-chaired by Hartung.

Funding for the research was provided by the Transatlantic Think Tank for Toxicology.

Tim Parsons | Newswise Science News
Further information:
http://www.jhsph.edu

Further reports about: Animal Animal Testing CAAT Chemical Health Legislation REACH Toxicology chemicals commercial chemicals drugs pesticides

More articles from Life Sciences:

nachricht Transport of molecular motors into cilia
28.03.2017 | Aarhus University

nachricht Asian dust providing key nutrients for California's giant sequoias
28.03.2017 | University of California - Riverside

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Challenging European Research Project to Develop New Tiny Microscopes

The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.

To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Transport of molecular motors into cilia

28.03.2017 | Life Sciences

A novel hybrid UAV that may change the way people operate drones

28.03.2017 | Information Technology

NASA spacecraft investigate clues in radiation belts

28.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>