For biological and biomedical research, science depends on animal experiments. The understanding of complex processes in the body such as, for example, the reaction of the immune system to certain viruses or the control of brain functions sometimes also requires experiments with monkeys, the so-called non-human primates.
EUPRIM-Net, a network consisting of eight European research centers, faces up to the special challenges of research with these animals. Under the leadership of the German Primate Center (DPZ) in Göttingen, Germany, EUPRIM-Net wants to advance the standards and methods of husbandry and breeding of primates, support the education in this area and to reduce the number of animal experiments by an increased exchange of samples. The EU will sponsor the continuation of this project, which was initiated in 2006, with seven million Euros for the next four years.
“New scientific knowledge from research with primates is an integral basis for advances in the fields of medicine, biology and biotechnology. It therefore contributes to keep our health on a high level and to develop new therapies,“ Stefan Treue, Director of the German Primate Center (DPZ) and spokesman of EUPRIM-Net said. Research makes use of various methods, including animal experiments. Owing to their closeness to human beings as regards genetics and behavioral biology, primates occupy a special position in this context. They are only used for experimental purposes if alternative methods are not available. Research with animals follows the 3R (“Refinement“, “Reduction“, “Replacement“) principle. This means that efforts have to be made to improve the experimental methods in order to reduce the number of animals used and that if possible, alternative methods are to be developed and employed.
This is the starting point for the European network EUPRIM-Net. Under DPZ leadership, eight primate institutions from six countries joined together in the year 2006. “We wanted to combine the competences of the individual institutions, refine and unify standards for the keeping, breeding and caring of the primates and thus ensure that experimental research with primates in Europe conforms with highest standards ,“ Stefan Treue said.
Owing to the great success of EUPRIM-Net, the EU will provide additional subsidies to the total amount of seven million Euros from 2011 to 2015. The network shall be supplemented by additional primate institutions and partners from the industrial sector and extended beyond European borders in future.
It is the aim of joint research projects to optimize and standardize husbandry and breeding of the animals as well as diagnosis and treatment of their diseases. The participating centers offer European research cost-free access to their bio banks, that is to their collections of DNA, tissue and blood samples as well as to their method inventory. In this way, new research approaches are possible and the number of animal experiments can be reduced. An important matter of concern for EUPRIM-Net is the training of technical and scientific staff with regard to the biology of primates and how to handle them in human care. For this purpose, several international advanced trainings have already been carried out and a DVD on primate training was produced and distributed to more than 100 research institutions.
Another emphasis in EUPRIM-Net is put on the investigation of methods, which could be employed as an alternative to animal experiments. “Experiments with primates will be irreplaceable for foreseeable times, however, our research contributes to the development of alternatives,“ Stefan Treue said.
From 23 to 25 November 2010 an international meeting will take place at the German Primate Center in order to discuss joint research projects.
Additional information about EUPRIM-Net at: http://www.euprim-net.euContact:
Cnidarians remotely control bacteria
21.09.2017 | Christian-Albrechts-Universität zu Kiel
Immune cells may heal bleeding brain after strokes
21.09.2017 | NIH/National Institute of Neurological Disorders and Stroke
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
19.09.2017 | Event News
12.09.2017 | Event News
06.09.2017 | Event News
21.09.2017 | Physics and Astronomy
21.09.2017 | Life Sciences
21.09.2017 | Health and Medicine