For biological and biomedical research, science depends on animal experiments. The understanding of complex processes in the body such as, for example, the reaction of the immune system to certain viruses or the control of brain functions sometimes also requires experiments with monkeys, the so-called non-human primates.
EUPRIM-Net, a network consisting of eight European research centers, faces up to the special challenges of research with these animals. Under the leadership of the German Primate Center (DPZ) in Göttingen, Germany, EUPRIM-Net wants to advance the standards and methods of husbandry and breeding of primates, support the education in this area and to reduce the number of animal experiments by an increased exchange of samples. The EU will sponsor the continuation of this project, which was initiated in 2006, with seven million Euros for the next four years.
“New scientific knowledge from research with primates is an integral basis for advances in the fields of medicine, biology and biotechnology. It therefore contributes to keep our health on a high level and to develop new therapies,“ Stefan Treue, Director of the German Primate Center (DPZ) and spokesman of EUPRIM-Net said. Research makes use of various methods, including animal experiments. Owing to their closeness to human beings as regards genetics and behavioral biology, primates occupy a special position in this context. They are only used for experimental purposes if alternative methods are not available. Research with animals follows the 3R (“Refinement“, “Reduction“, “Replacement“) principle. This means that efforts have to be made to improve the experimental methods in order to reduce the number of animals used and that if possible, alternative methods are to be developed and employed.
This is the starting point for the European network EUPRIM-Net. Under DPZ leadership, eight primate institutions from six countries joined together in the year 2006. “We wanted to combine the competences of the individual institutions, refine and unify standards for the keeping, breeding and caring of the primates and thus ensure that experimental research with primates in Europe conforms with highest standards ,“ Stefan Treue said.
Owing to the great success of EUPRIM-Net, the EU will provide additional subsidies to the total amount of seven million Euros from 2011 to 2015. The network shall be supplemented by additional primate institutions and partners from the industrial sector and extended beyond European borders in future.
It is the aim of joint research projects to optimize and standardize husbandry and breeding of the animals as well as diagnosis and treatment of their diseases. The participating centers offer European research cost-free access to their bio banks, that is to their collections of DNA, tissue and blood samples as well as to their method inventory. In this way, new research approaches are possible and the number of animal experiments can be reduced. An important matter of concern for EUPRIM-Net is the training of technical and scientific staff with regard to the biology of primates and how to handle them in human care. For this purpose, several international advanced trainings have already been carried out and a DVD on primate training was produced and distributed to more than 100 research institutions.
Another emphasis in EUPRIM-Net is put on the investigation of methods, which could be employed as an alternative to animal experiments. “Experiments with primates will be irreplaceable for foreseeable times, however, our research contributes to the development of alternatives,“ Stefan Treue said.
From 23 to 25 November 2010 an international meeting will take place at the German Primate Center in order to discuss joint research projects.
Additional information about EUPRIM-Net at: http://www.euprim-net.euContact:
Unique genome architectures after fertilisation in single-cell embryos
30.03.2017 | IMBA - Institut für Molekulare Biotechnologie der Österreichischen Akademie der Wissenschaften GmbH
Transport of molecular motors into cilia
28.03.2017 | Aarhus University
The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
30.03.2017 | Physics and Astronomy
30.03.2017 | Studies and Analyses
30.03.2017 | Life Sciences