Scientists from the University of Basel have now discovered that a genetic factor for good memory is also associated with a heightened risk for the development of a posttraumatic stress disorder in war victims. The findings of this study will be published this week in the American journal PNAS.
There are many advantages of having a good memory. Retaining what has been learned at school comes more easily, for example, or keys are less likely to be misplaced. But having a good memory could also have a downside, namely, when shocking experiences, such as a severe accident or a rape incident, are deeply engraved into the brain. When such traumatic experiences continue to exist as painful memories, they could increase the chance of a posttraumatic stress disorder developing.
Dominique de Quervain and Andreas Papassotiropoulos, from the transfaculty research platform "Molecular and Cognitive Neurosciences" and the Biozentrum of the University of Basel, have recently discovered that car al and neutral information were likewise better remembered. Furthermore, the scientists have found that the gene variant is associated with heightened activity in memory relevant regions of the brain. More than 1000 healthy persons took part in this study in Basel.
In a second part of this study, the researchers, together with the scientists Thomas Elbert from Konstanz and Iris-Tatjana Kolassa from Ulm, investigated the effect of the gene variant on traumatic memories in around 350 survivors of the genocide in Rwanda. The scientists found that the carriers of the identified gene variant experienced more distressing memories of the shocking events during the civil war and were more likely to suffer a posttraumatic stress disorder.
This study was able to show, for the first time, a genetic link between good memory and a heightened risk for psychological trauma and suggests that PKC alpha plays an important role in the regulation of memory processes. The current study was undertaken as part of a project directed by de Quervain and Papassotiropoulos.Neurobiological mechanism of human memory
PNAS 2012 ; published ahead of print May 14, 2012 | doi:10.1073/pnas.1200857109Media contact
Prof. Dr. Dominique J.-F. de Quervain, University of Basel, Division of Cognitive Neuroscience, Tel:+41 61 267 0237 (direct), +41 61 267 02 38 (secretary), E-mail: firstname.lastname@example.org
Reto Caluori | idw
Further reports about: > Basel > Cognitive Neuroscience > Cognitive Science > Downside > Molecular Target > Neuroscience > biological mechanism > gene variant > human memory > molecular mechanism > posttraumatic stress > posttraumatic stress disorder > traumatic experience > traumatic stress disorder
Biochemical 'fingerprints' reveal diabetes progression
22.08.2017 | Umea University
When fish swim in the holodeck
22.08.2017 | University of Vienna
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
16.08.2017 | Event News
04.08.2017 | Event News
26.07.2017 | Event News
22.08.2017 | Life Sciences
22.08.2017 | Life Sciences
22.08.2017 | Life Sciences