Apply the ointment, light on, light off – that’s how easy it is to cure various forms of non-melanoma skin cancer.
Cells that are incubated with aminolevulinic acid form protoporphyrin IX (PpIX), which appears red on the fluorescence micrograph. Both nerve cells (top row), and skin cancer cells (bottom row) form PpIX. The image on the left of both rows represents an overview, the images in the middle and on the right show enlarged sections of the images on the left. The power plants of the nerve and cancer cells, the mitochondria, are coloured green. The colour pattern of PpIX and the mitochondrial dye are similar. This suggests that PpIX accumulates in the mitochondria. Image: Ben Novak
However, the majority of patients suffer severe pain during the so-termed photodynamic therapy. Why the treatment with ointment and red light can be so painful has now been uncovered by researchers from the RUB.They identified the ion channels involved and signalling molecules secreted by the cancer cells. “The results may provide a starting point for suppressing the pain”, says Dr. Ben Novak of the Department of Animal Physiology.
Dr. Josef König | idw
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Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
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The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
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With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
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An interdisciplinary group of researchers interfaced individual bacteria with a computer to build a hybrid bio-digital circuit - Study published in Nature Communications
Scientists at the Institute of Science and Technology Austria (IST Austria) have managed to control the behavior of individual bacteria by connecting them to a...
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