Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


DNA motor 'walks' along nanotube, transports tiny particle

Researchers have created a new type of molecular motor made of DNA and demonstrated its potential by using it to transport a nanoparticle along the length of a carbon nanotube.

The design was inspired by natural biological motors that have evolved to perform specific tasks critical to the function of cells, said Jong Hyun Choi, a Purdue University assistant professor of mechanical engineering.

Whereas biological motors are made of protein, researchers are trying to create synthetic motors based on DNA, the genetic materials in cells that consist of a sequence of four chemical bases: adenine, guanine, cytosine and thymine.

The walking mechanism of the synthetic motors is far slower than the mobility of natural motors. However, the natural motors cannot be controlled, and they don't function outside their natural environment, whereas DNA-based motors are more stable and might be switched on and off, Choi said.

"We are in the very early stages of developing these kinds of synthetic molecular motors," he said.

New findings were detailed in a research paper published this month in the journal Nature Nanotechnology.

In coming decades, such molecular motors might find uses in drug delivery, manufacturing and chemical processing.

The new motor has a core and two arms made of DNA, one above and one below the core. As it moves along a carbon-nanotube track it continuously harvests energy from strands of RNA, molecules vital to a variety of roles in living cells and viruses.

The Nature Nanotechnology paper was authored by graduate students Tae-Gon Cha, Jing Pan and Haorong Chen; former undergraduate student Janette Salgado; graduate student Xiang Li; Chengde Mao, a professor of chemistry; and Choi.

"Our motors extract chemical energy from RNA molecules decorated on the nanotubes and use that energy to fuel autonomous walking along the carbon nanotube track," Choi said.

The core is made of an enzyme that cleaves off part of a strand of RNA. After cleavage, the upper DNA arm moves forward, binding with the next strand of RNA, and then the rest of the DNA follows. The process repeats until reaching the end of the nanotube track.

Researchers used the motor to move nanoparticles of cadmium disulfide along the length of a nanotube. The nanoparticle is about 4 nanometers in diameter.

The researchers combined two fluorescent imaging systems to document the motor's movement, one in the visible spectrum and the other in the near-infrared range. The nanoparticle is fluorescent in visible light and the nanotubes are fluorescent in the near-infrared.

The motor took about 20 hours to reach the end of the nanotube, which was several microns long, but the process might be sped up by changing temperature and pH, a measure of acidity.

This work has been supported by the U.S. Office of Naval Research.

Writer: Emil Venere, 765-494-4709,

Source: Jong Hyun Choi, 765-496-3562,

Note to Journalists: An electronic or hard copy of the research paper is available by contacting Nature at or calling 212-726-9231.

Emil Venere | EurekAlert!
Further information:,-transports-tiny-particle.html

More articles from Life Sciences:

nachricht First time-lapse footage of cell activity during limb regeneration
25.10.2016 | eLife

nachricht Phenotype at the push of a button
25.10.2016 | Institut für Pflanzenbiochemie

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Etching Microstructures with Lasers

Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.

This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Ice shelf vibrations cause unusual waves in Antarctic atmosphere

25.10.2016 | Earth Sciences

Fluorescent holography: Upending the world of biological imaging

25.10.2016 | Power and Electrical Engineering

Etching Microstructures with Lasers

25.10.2016 | Process Engineering

More VideoLinks >>>