Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Different eggs in adolescent girls and adult women


Are the eggs produced by adolescent girls the same as the ones produced by adult women?

A recent study published in Human Molecular Genetics by Professor Kui Liu from the University of Gothenburg in Sweden shows compelling evidence that there are two completely distinct types of eggs in the mammalian ovary – “the first wave” and “the adult wave”.

Different eggs in adolescent girls and adult women

Professor Liu’s team used two genetically modified mouse models to show that the first wave of eggs, which starts immediately after birth, contributes to the onset of puberty and provides fertilizable eggs into the transition from adolescence to adulthood.

In contrast, the adult wave remains in a state of dormancy until activated during the adult life and then provides eggs throughout the entire reproductive lifespan.

This is the first time that the developmental dynamics of two distinct populations of eggs have been clearly described in an animal model, and there is evidence that these two waves of eggs most likely also exist in the human ovary.

The identification and characterization of the two waves of eggs will lead to new ways of thinking about how to obtain the best eggs when treating women for ovarian diseases that cause infertility. Such techniques will prove especially useful for women suffering from premature ovarian failure (POF), which affects 1%–4% of all women of childbearing age.

The results may also lead to more effective treatments for ovarian diseases by specifically targeting the different egg populations.

Dr. Liu is a professor at the Department of Chemistry and Molecular Biology, University of Gothenburg. His research group specializes in the development of female germ cells. His work in recent years has focused on translating the results from animal models into clinical techniques for treating female infertility.

For more information, please contact Professor Kui Liu: Tel. +46 (0)073- 62 05 064;

Weitere Informationen:

Carina Eliasson | idw - Informationsdienst Wissenschaft

Further reports about: Molecular eggs evidence infertility ovarian populations waves women

More articles from Life Sciences:

nachricht Atom-Sized Craters Make a Catalyst Much More Active
30.11.2015 | SLAC National Accelerator Laboratory

nachricht Hydra Can Modify Its Genetic Program
30.11.2015 | Université de Genève (University of Geneva)

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: How Cells in the Developing Ear ‘Practice’ Hearing

Before the fluid of the middle ear drains and sound waves penetrate for the first time, the inner ear cells of newborn rodents practice for their big debut. Researchers at Johns Hopkins report they have figured out the molecular chain of events that enables the cells to make “sounds” on their own, essentially “practicing” their ability to process sounds in the world around them.

The researchers, who describe their experiments in the Dec. 3 edition of the journal Cell, show how hair cells in the inner ear can be activated in the absence...

Im Focus: Climate study finds evidence of global shift in the 1980s

Planet Earth experienced a global climate shift in the late 1980s on an unprecedented scale, fuelled by anthropogenic warming and a volcanic eruption, according to new research published this week.

Scientists say that a major step change, or ‘regime shift’, in the Earth’s biophysical systems, from the upper atmosphere to the depths of the ocean and from...

Im Focus: Innovative Photovoltaics – from the Lab to the Façade

Fraunhofer ISE Demonstrates New Cell and Module Technologies on its Outer Building Façade

The Fraunhofer Institute for Solar Energy Systems ISE has installed 70 photovoltaic modules on the outer façade of one of its lab buildings. The modules were...

Im Focus: Lactate for Brain Energy

Nerve cells cover their high energy demand with glucose and lactate. Scientists of the University of Zurich now provide new support for this. They show for the first time in the intact mouse brain evidence for an exchange of lactate between different brain cells. With this study they were able to confirm a 20-year old hypothesis.

In comparison to other organs, the human brain has the highest energy requirements. The supply of energy for nerve cells and the particular role of lactic acid...

Im Focus: Laser process simulation available as app for first time

In laser material processing, the simulation of processes has made great strides over the past few years. Today, the software can predict relatively well what will happen on the workpiece. Unfortunately, it is also highly complex and requires a lot of computing time. Thanks to clever simplification, experts from Fraunhofer ILT are now able to offer the first-ever simulation software that calculates processes in real time and also runs on tablet computers and smartphones. The fast software enables users to do without expensive experiments and to find optimum process parameters even more effectively.

Before now, the reliable simulation of laser processes was a job for experts. Armed with sophisticated software packages and after many hours on computer...

All Focus news of the innovation-report >>>



Event News

Urbanisation and migration from rural areas challenging agriculture in Eastern Europe

30.11.2015 | Event News

Fraunhofer’s Urban Futures Conference: 2 days in the city of the future

25.11.2015 | Event News

Gluten oder nicht Gluten? Überempfindlichkeit auf Weizen kann unterschiedliche Ursachen haben

17.11.2015 | Event News

Latest News

Teamplay IT solution enables more efficient use of protocols

30.11.2015 | Trade Fair News

Greater efficiency and potentially reduced costs with new MRI applications

30.11.2015 | Trade Fair News

Modular syngo.plaza as a comprehensive solution – even for enterprise radiology

30.11.2015 | Trade Fair News

More VideoLinks >>>