Prof. Eugene “Gene” Myers, one of the pioneers in bioinformatics, is affiliated with the group as a mentor. Together with his laboratory at the Max Planck Center for Systems Biology in Dresden, the junior group will decipher and compare the genetic codes of several flatworm species.
Flatworms are masters of regeneration, and are, therefore, interesting for scientists: If they are cut in two pieces, each half will develop into a new worm. By comparing the genetic material, researchers hope to gain new insights into regeneration of tissue that could have a huge impact on medicine.A new junior research group for Computational Biology (CBI) has been established at Heidelberg Institute for Theoretical Studies (HITS). It complements the work of the other six research groups, which carry out basic research in different fields of science. The focus lies on the processing and structuring of large data volumes. The leader of the new group is Dr. Siegfried Schloissnig, a 33-year-old Computer Scientist with a Doctorate in Human Biology, who previously worked as a PostDoc at the European Molecular Biology Laboratory (EMBL). A PostDoc and two PhD students will work under his leadership in Heidelberg.
New approaches to the de novo assemblyThe new junior research group at HITS will also work on these objectives in collaboration with Gene Myers’ laboratory in Dresden and the recently established Dresden Genome Center. Together with his group, Siegfried Schloissnig will develop new approaches to the so-called de novo assembly, which is the reconstruction of genome sequences by means of DNA sequencers and bioinformatic methods. In the course of sequencing by standard methods, DNA is copied multiple times. These copies are randomly split up into numerous small fragments. These fragments are examined for overlaps by means of bioinformatic methods and are subsequently reassembled. The smaller the fragments and the more complex the genome of interest, the more complicated is the problem. The situation becomes even more difficult, when no comparable genome is available and researchers have to assemble the genome de novo, i.e. anew. This is exactly the case with flatworms, whose genetic codes the HITS junior group plans to decipher.
Dr. Peter Saueressig | idw
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02.12.2016 | IMBA - Institut für Molekulare Biotechnologie der Österreichischen Akademie der Wissenschaften GmbH
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
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The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
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The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.
Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...
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