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Cutting off the oxygen supply to serious diseases

31.01.2012
A new family of proteins which regulate the human body’s ‘hypoxic response’ to low levels of oxygen has been discovered by scientists at Barts Cancer Institute at Queen Mary, University of London and The University of Nottingham.

The discovery has been published in the international journal Nature Cell Biology. It marks a significant step towards understanding the complex processes involved in the hypoxic response which, when it malfunctions, can cause and affect the progress of many types of serious disease, including cancer.

The researchers have uncovered a previously unknown level of hypoxic regulation at a molecular level in human cells which could provide a novel pathway for the development of new drug therapeutics to fight disease. The cutting-edge work was funded by the Biotechnology and Biological Sciences Research Council (BBSRC).

More information is available from Dr Tyson Sharp, Barts Cancer Institute, Queen Mary University of London : +44 (0)20 7882 3848 t.sharp@qmul.ac.uk or Kerry Noble, Communications Manager at Queen Mary, University of London, on +44 (0)20 7882 7943, k.noble@qmul.ac.uk

Emma Rayner - Media Relations Manager
Email: emma.rayner@nottingham.ac.uk
Phone: +44 (0)115 951 5793
Location: King's Meadow Campus

Emma Rayner | EurekAlert!
Further information:
http://www.nottingham.ac.uk

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