Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New Collaborative Research Centre in Molecular Biology

01.06.2012
DFG provides over ten million Euros to fund CRC “Cellular Quality Control and Damage Response”

How do cells respond to damage and how are disturbances in cellular equilibrium avoided or compensated? These issues are at the heart of a new Collaborative Research Centre funded by the German Research Foundation (DFG) and ready to be launched at Heidelberg University on 1 July 2012.

The CRC 1036 “Cellular Quality Control and Damage Response” is coordinated by Prof. Dr. Bernd Bukau, director of the Center for Molecular Biology of Heidelberg University (ZMBH). In the course of the next four years, this new research venture will receive funding to the tune of over ten million Euros.

The 17 research projects constituting CRC 1036 focus on the molecular mechanisms of cellular quality control. Despite their complexity, biological processes normally function with incredible precision, says Prof. Bukau. Nevertheless, the underlying processes are subject to occasional errors aggravated by external chemical or physical stress factors. In response to these mishaps, the cells of all organisms have developed efficient networks of surveillance systems operating at the levels of macromolecules, cellular compartments, cells and organs. “These networks minimise and reverse damage caused by process deficiencies and defective molecules”, Prof. Bukau adds.

At the levels of the genome, the transcriptome and the proteome, the Heidelberg research groups involved in CRC 1036 intend to investigate how biological surveillance systems avoid errors and damage and how repair systems detect and handle defects. “A comprehensive understanding of these systems will also give us new insights into the genesis of diseases and the course of the cellular aging process”, Prof. Bukau emphasises. The new Collaborative Research Centre assembles Heidelberg University scientists working in biosciences and medicine, as well as researchers from the German Cancer Research Center (DKFZ) and the European Molecular Biology Laboratory (EMBL) in Heidelberg. Prof. Bukau heads a cross-departmental group at the DKFZ and is co-director of the DKFZ-ZMBH Alliance.

At present, Heidelberg University receives funding for eight Collaborative Research Centres. In addition, there are five CRC/Transregio with key Heidelberg participation, four of them with coordinators from the university. Alongside CRC 1036, the German Research Foundation has also approved the establishment of CRC/TRR 125 “Cognition-Guided Surgery” starting up on 1 July 2012. Coordinator is the Heidelberg medical scientist Prof. Dr. Markus W. Büchler.

Contact
Prof. Dr. Bernd Bukau
Center for Molecular Biology of Heidelberg University (ZMBH)
Phone: +49 6221 54-6850
direktor@zmbh.uni-heidelberg.de
Communications and Marketing
Press Office, phone: +49 6221 54-2311
presse@rektorat.uni-heidelberg.de

Marietta Fuhrmann-Koch | idw
Further information:
http://www.dfg.de
http://www.uni-heidelberg.de

More articles from Life Sciences:

nachricht How brains surrender to sleep
23.06.2017 | IMP - Forschungsinstitut für Molekulare Pathologie GmbH

nachricht A new technique isolates neuronal activity during memory consolidation
22.06.2017 | Spanish National Research Council (CSIC)

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Quantum thermometer or optical refrigerator?

23.06.2017 | Physics and Astronomy

A 100-year-old physics problem has been solved at EPFL

23.06.2017 | Physics and Astronomy

Equipping form with function

23.06.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>