Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Change in temperature uncovers genetic cross talk in plant immunity

16.11.2010
University of Missouri investigators' discovery sheds light on how plants fight off bacterial infections

Like us, plants rely on an immune system to fight off disease. Proteins that scout out malicious bacterial invaders in the cell and communicate their presence to the nucleus are important weapons in the plant's disease resistance strategy.

Researchers at the University of Missouri recently "tapped" into two proteins' communications with the nucleus and discovered a previously unknown level of cross talk. The discovery adds important new information about how plant proteins mediate resistance to bacteria that cause disease and may ultimately lead to novel strategies for boosting a plant's immune system.

Special proteins in the plant, called resistance proteins, can recognize highly specific features of proteins from pathogen, called effector proteins. When a pathogen is detected, a resistance protein triggers an "alarm" that communicates the danger to the cell's nucleus. The communication between the resistance protein and nucleus occurs through a mechanism called a signaling pathway.

"The signaling pathway is like a telephone wire that stretches between each resistance protein all the way to the nucleus," said Walter Gassmann, senior author of the study and associate professor of plant sciences in the Christopher S. Bond Life Sciences Center at the University. "Until now, evidence suggested that, among certain classes of resistance proteins, these wires don't cross -- one resistance protein can't hear what another one is saying."

But in a recent study, Gassmann and his MU colleagues -- post-doctoral researchers Sang Hee Kim and Saikat Bhattacharjee, graduate students Fei Gao and Ji Chul Nam, and former undergraduate student Joe Adiasor -- "tapped" into these lines and found evidence for cross talk between two different resistance proteins.

The discovery was made while studying another plant protein, SRFR1, which helps to moderate the immune response of the wild mustard plant Arabidopsis thaliana to the bacterial pathogen Pseudomonas syringae. The researchers were interested in why removal of the SRFR1 gene resulted in a plant with an immune system that was always activated. They traced the effect back to expression of the resistance protein, SNC1.

"The connection between SRFR1 and SNC1 was somewhat surprising," said Gassmann. "We identified SRFR1 based on its effect on the plant immune response to the bacterial effector protein AvrRps4, which is usually detected by the resistance protein RPS4, not SNC1."

This class of plant resistance proteins has been thought to be highly specific detectors, meaning each member responds to a different effector protein.

"Based on our work, we think part of the answer is that both SNC1 and RPS4 physically associate with SRFR1. In other words, SRFR1 is where the SNC1 and RPS4 telephone wires get crossed."

The researchers tapped into this cross talk while studying temperature effects on resistance. They found that both proteins, SNC1 and RPS4, contribute to detection of AvrRps4 at 22 degrees Celsius, but only RPS4 does so at 24 degrees Celsius. Gassmann speculated that the temperature dependence may explain why this cross talk had not been previously observed.

"The discovery adds important new knowledge about the underlying mechanism of how plants fight off bacterial infection," said Gassmann, who is also a member of the University's Interdisciplinary Plant Group.

The new research was funded by the National Science Foundation and is reported in the November 4 issue of PLoS Pathogens.

Melody Kroll | EurekAlert!
Further information:
http://www.missouri.edu

More articles from Life Sciences:

nachricht Symbiotic bacteria: from hitchhiker to beetle bodyguard
28.04.2017 | Johannes Gutenberg-Universität Mainz

nachricht Nose2Brain – Better Therapy for Multiple Sclerosis
28.04.2017 | Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik IGB

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Fighting drug resistant tuberculosis – InfectoGnostics meets MYCO-NET² partners in Peru

28.04.2017 | Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

 
Latest News

Wireless power can drive tiny electronic devices in the GI tract

28.04.2017 | Medical Engineering

Ice cave in Transylvania yields window into region's past

28.04.2017 | Earth Sciences

Nose2Brain – Better Therapy for Multiple Sclerosis

28.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>