New research appearing online today in Clinical Chemistry, the journal of AACC, shows that a handheld mobile device can check patients’ HIV status with just a finger prick, and synchronize the results in real time with electronic health records. This technology takes a step toward providing remote areas of the world with diagnostic services traditionally available only in centralized healthcare settings.
Of the 34 million people infected with HIV worldwide, 68% of them live in sub-Saharan Africa, with South and Southeast Asia bearing the second greatest burden of disease. Many HIV-infected people in these regions are unable to get tested or treated because they can’t easily travel to centralized healthcare centers. This creates an extreme economic burden on already-poor nations, with the epidemic estimated to cause a 1.5% annual loss in gross domestic product each year for the worst-affected countries. It has also created 16.6 million AIDS orphans—children who have lost one or both parents to the disease.
A low-cost mobile device that performs HIV testing could help combat these trends, and the overall global epidemic, by enabling the diagnosis and treatment of HIV-infected people in resource-limited settings. In this study, a team including Curtis D. Chin, PhD, and Yuk Kee Cheung, PhD, designed a device that captures all the essential functions of enzyme-linked immunosorbent assays, the most commonly used laboratory diagnostic for HIV. The authors show that the device performs laboratory-quality HIV testing in 15 minutes using finger-pricked whole blood.
The device also detects weakly positive samples, and uses cellphone and satellite networks to automatically synchronize test results with patient health records from anywhere in the world. Because of this real-time data upload, this mobile device will allow policymakers and epidemiologists to monitor disease prevalence across geographical regions quickly and effectively. This could improve effectiveness in allocating medications to different communities, and patient care in general.Dr. Nader Rifai, editor in chief of Clinical Chemistry, states, "This is a perfect example of how ingenuity and good science can effectively address a real and serious medical problem."
Clinical Chemistry is the leading international journal of clinical laboratory science, providing 2,000 pages per year of peer-reviewed papers that advance the science of the field. With an impact factor of 7.9, Clinical Chemistry covers everything from molecular diagnostics to laboratory management.
Molly Polen | Newswise
Repairing damaged hearts with self-healing heart cells
22.08.2017 | National University Health System
Biochemical 'fingerprints' reveal diabetes progression
22.08.2017 | Umea University
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
16.08.2017 | Event News
04.08.2017 | Event News
26.07.2017 | Event News
22.08.2017 | Health and Medicine
22.08.2017 | Materials Sciences
22.08.2017 | Life Sciences