Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Biotransformed blueberry juice fights fat and diabetes

02.09.2009
New study published in the International Journal of Obesity

Juice extracted from North American lowbush blueberries, biotransformed with bacteria from the skin of the fruit, holds great promise as an anti-obesity and anti-diabetic agent.

The study, published in the International Journal of Obesity, was conducted by researchers from the Université de Montréal, the Institut Armand-Frappier and the Université de Moncton who tested the effects of biotransformed juices compared to regular blueberry drinks on mice.

"Results of this study clearly show that biotransformed blueberry juice has strong anti-obesity and anti-diabetic potential," says senior author Pierre S. Haddad, a pharmacology professor at the Université de Montréal's Faculty of Medicine. "Biotransformed blueberry juice may represent a novel therapeutic agent, since it decreases hyperglycemia in diabetic mice and can protect young pre-diabetic mice from developing obesity and diabetes."

The scientists tested the effect of biotransformed blueberry juice on a group of mice prone to obesity, insulin resistance, diabetes and hypertension. Incorporating biotransformed blueberry juice into the water of mice reduced their food intake and their body weight. "These mice were an excellent model that closely resembles obesity and obesity-linked type 2 diabetes in humans," says Dr. Haddad, who is also director of the CIHR Team in Aboriginal Anti-Diabetic Medicines at the Université de Montréal.

Biotransformation of the blueberry juice was achieved with a new strain of bacteria isolated from the blueberry flora, specifically called Serratia vaccinii, which increases the fruit's antioxidant effects. "The identification of the active compounds in biotransformed blueberry juice may result in the discovery of promising new antiobesity and antidiabetic molecules," says Dr. Haddad.

As for the impact of blueberry products on diabetes, says Tri Vuong, lead author and recent PhD graduate from the Université de Montréal's Department of Pharmacology: "Consumption of fermented blueberry juice gradually and significantly reduced high blood glucose levels in diabetic mice. After three days, our mice subjects reduced their glycemia levels by 35 percent."

About the Study:

The article "Antiobesity and antidiabetic effects of biotransformed blueberry juice in KKAy mice," published in the International Journal of Obesity, was authored by Tri Vuong, Ali Benhaddou-Andaloussi, Antoine Breault , Despina Harbilas, Louis C. Martineau, Pierre S. Haddad of the Université de Montréal and Diane Vallerand, C. Ramassamy of the Institut Armand-Frappier, C. Matar of the Université de Moncton.

Partners in Research:

This study was funded by the Canadian Institutes of Health Research, the Atlantic Canada Opportunities Agency and the Fonds de recherche sur la nature et les technologies.

On the Web:

About cited article from the International Journal of Obesity: http://www.nature.com/ijo/journal/vaop/ncurrent/full/ijo2009149a.html

About the Université de Montréal's Department of Pharmacology: http://www.pharmco.umontreal.ca

About Pierre S. Haddad: www.pharmco.umontreal.ca/apropos/LaboHaddad/LabHaddad.htm

About the INRS-Institut Armand-Frappier: www.iaf.inrs.ca

About the Université de Moncton: www.umoncton.ca

For more information, please contact:
Sylvain-Jacques Desjardins
International press attaché
Université de Montréal
Telephone: 514-343-7593
Email: sylvain-jacques.desjardins@umontreal.ca

Sylvain-Jacques Desjardins | EurekAlert!
Further information:
http://www.umontreal.ca

More articles from Life Sciences:

nachricht Antimicrobial substances identified in Komodo dragon blood
23.02.2017 | American Chemical Society

nachricht New Mechanisms of Gene Inactivation may prevent Aging and Cancer
23.02.2017 | Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut e.V. (FLI)

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

From rocks in Colorado, evidence of a 'chaotic solar system'

23.02.2017 | Physics and Astronomy

'Quartz' crystals at the Earth's core power its magnetic field

23.02.2017 | Earth Sciences

Antimicrobial substances identified in Komodo dragon blood

23.02.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>