Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Balance organs affect brain blood flow

24.09.2009
The organs of the inner ear have a direct effect on brain blood flow, independent of blood pressure and CO2 levels in the blood. Researchers writing in the open access journal BMC Neuroscience used a series of human centrifuge experiments to investigate the effects of stimulation of the otoliths and semi-circular canals on cerebrovascular response.

Dr. Jorge Serrador, from Harvard Medical School, worked with a team of researchers, including NASA scientists, to carry out the tests. He said, "While a role for the vestibular system in the autonomic response to position has been documented, this is the first study to demonstrate a direct effect of otolith stimulation on cerebral blood flow".

The researchers stimulated the vestibular organs of 25 healthy people by tilting them forwards and backwards, and by translation on a centrifuge. Changes in cerebral flow velocity were dependent on the frequency of vestibular stimulation and were in opposition to changes in blood pressure and not directly related to changes in end tidal CO2.

Speaking about the implications of these results, Serrador said, "Standing up places the head above the heart and thus makes it harder to provide blood flow to the brain. Having a connection between the otoliths, which tell us that we are standing, and the cerebrovasculature may be part of the adaption that allows us to maintain our brain blood flow when upright. This connection might explain the reduced cerebral blood flow in some people. For example, aging is associated with vestibular loss that might contribute to reductions in global cerebral blood flow. Similarly, patients with orthostatic intolerance could have underlying vestibular impairment that exacerbates cerebral hypoperfusion when upright. The knowledge gained from this study might lead to new treatment options for these conditions".

Notes to Editors

1. Vestibular effects on cerebral blood flow
Jorge M Serrador, Todd T Schlegel, F Owen Black and Scott J Wood
BMC Neuroscience (in press)
2. BMC Neuroscience is an open access journal publishing original peer-reviewed research articles in all aspects of the nervous system, including molecular, cellular, developmental and animal model studies, as well as cognitive and behavioral research, and computational modeling. BMC Neuroscience (ISSN 1471-2202) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, PsycINFO, Thomson Reuters (ISI) and Google Scholar.

3. BioMed Central (http://www.biomedcentral.com/) is an STM (Science, Technology and Medicine) publisher which has pioneered the open access publishing model. All peer-reviewed research articles published by BioMed Central are made immediately and freely accessible online, and are licensed to allow redistribution and reuse. BioMed Central is part of Springer Science+Business Media, a leading global publisher in the STM sector

Graeme Baldwin | EurekAlert!
Further information:
http://www.biomedcentral.com

More articles from Life Sciences:

nachricht A Map of the Cell’s Power Station
18.08.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau

nachricht On the way to developing a new active ingredient against chronic infections
18.08.2017 | Deutsches Zentrum für Infektionsforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

A Map of the Cell’s Power Station

18.08.2017 | Life Sciences

Engineering team images tiny quasicrystals as they form

18.08.2017 | Physics and Astronomy

Researchers printed graphene-like materials with inkjet

18.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>