Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Bacterial Genome May Hold Answers to Mercury Mystery

12.04.2011
A newly sequenced bacterial genome from a team led by the Department of Energy’s Oak Ridge National Laboratory could contain clues as to how microorganisms produce a highly toxic form of mercury.

Methylmercury, a potent human neurotoxin, appears in the environment when certain naturally occurring bacteria transform inorganic mercury into its more toxic cousin. Few bacterial species are capable of this conversion, and exactly how the transformation takes place has been a matter of debate for decades.

“What is not known are the genes or the proteins that allow these bacteria to mediate the transformation,” said ORNL’s Steven Brown, who led a research team to sequence the genome of a bacterium in the Desulfovibrio genus that is capable of methylating mercury.

The new genome, sequenced at the California-based DOE Joint Genome Institute (JGI) and published in the Journal of Bacteriology, lays the foundation for future research to examine the little understood mechanisms behind the production of methylmercury.

Desulfovibrio desulfuricans strain ND132 is an organism that thrives in sediments and soils without oxygen – the places in lakes, streams and wetlands where mercury contamination is converted to methylmercury. It is representative of a group of organisms that “breathe” sulfate instead of oxygen and are largely responsible for mercury methylation in nature.

“This is the first Desulfovibrio genome that will methylate mercury that’s been published,” Brown said. “Now that we have this resource, we can take a comparative approach and look at what is different between the bacteria that can methylate mercury and those that are unable to.”

The introduction of mercury into the environment primarily stems from its use in industrial processes and from the burning of fossil fuels. Although industry and regulators have worked to minimize the release of mercury, there is a legacy of mercury pollution in aquatic environments worldwide. Understanding the fundamental science behind the production of methylmercury could eventually help mitigate and reduce the impacts of mercury pollution.

“Mercury is a global contaminant of concern,” Brown said. “We hope that some of the lessons we learn from these studies will be applicable to many sites. If we can identify the genes involved in mercury methylation, we hope to go to the local environment and understand more about the function and the ecology of the organisms and their gene products that mediate this transformation.”

The study was published as “Genome Sequence of the Mercury Methylating Strain Desulfovibrio desulfuricans ND132.” Collaborators included researchers from ORNL, the Smithsonian Environmental Research Center, the University of Missouri and Lawrence Berkeley National Laboratory’s JGI.

The research was supported by DOE’s Office of Science.

ORNL is managed by UT-Battelle for the Department of Energy's Office of Science.

Morgan McCorkle | Newswise Science News
Further information:
http://www.ornl.gov

More articles from Life Sciences:

nachricht Water forms 'spine of hydration' around DNA, group finds
26.05.2017 | Cornell University

nachricht How herpesviruses win the footrace against the immune system
26.05.2017 | Helmholtz-Zentrum für Infektionsforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

How herpesviruses win the footrace against the immune system

26.05.2017 | Life Sciences

Water forms 'spine of hydration' around DNA, group finds

26.05.2017 | Life Sciences

First Juno science results supported by University of Leicester's Jupiter 'forecast'

26.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>